HUS1 Protein (AA 1-280) (His tag)
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- 抗原 See all HUS1 蛋白
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-280
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This HUS1 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 产品特性
- HUS1, 1-280aa, Human, His tag, E.coli
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product HUS1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25mg/ml (determined by Bradford assay)
- 缓冲液
- Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 40% Glycerol
- 储存条件
- 4 °C
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- 抗原
- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
- 别名
- HUS1 (HUS1 产品)
- 别名
- hHUS1 Protein, mHus1 Protein, XHus1 Protein, hus1 Protein, HUS1 checkpoint clamp component Protein, checkpoint clamp complex protein Hus1 Protein, HUS1 checkpoint clamp component L homeolog Protein, HUS1 Protein, Hus1 Protein, hus1 Protein, hus1.L Protein
- 背景
- HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response. Recombinant human HUS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: checkpoint protein HUS1,. NCBI no.: NP_004498
- 分子量
- 33.8 kDa (300aa), confirmed by MALDI-TOF
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