CD200 Protein (CD200) (AA 31-236) (Fc Tag)
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- 抗原 See all CD200 蛋白
- CD200
- 蛋白类型
- Recombinant
- 产品特性
- AA 31-236
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宿主
- 小鼠
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资源
- CHO Cells
- 标记
- This CD200 protein is labelled with Fc Tag.
- 原理
- CD200 (mouse):Fc (mouse) (rec.) (non-lytic)
- 特异性
- The extracellular domain of mouse CD200 (aa 31-236) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a.
- 产品特性
- Protein. The extracellular domain of mouse CD200 (aa 31-236) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/μg protein (LAL test, Lonza). Lyophilized from 0.2μm-filtered solution in PBS. Purity: >98 % (SDS-PAGE). CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 knockout mice are characterized by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD200 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD200 homologs which are expressed on infected cells during the lytic phase. Like CD200 itself, viral CD200 homologs also suppress myeloid cell activity, enabling increased viral propagation.
- 纯度
- >98 % (SDS-PAGE)
- 内毒素水平
- <0.06EU/μg protein (LAL test, Lonza).
- Biological Activity Comment
- Shows the biological function of the CD200 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
- Top Product
- Discover our top product CD200 蛋白
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CD200 (CD200) (AA 31-232) protein (His tag)
CD200 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 (CD200) (AA 31-232) protein (Fc Tag)CD200 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 (CD200) protein (His tag)CD200 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
CD200 (CD200) (AA 56-257) protein (His tag)CD200 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD200 (CD200) (AA 31-232) protein (His tag)CD200 宿主: 人 宿主: HEK-293 Cells Recombinant >98 % as determined by SDS-PAGE.
CD200 (CD200) (AA 34-124) protein (GST tag)CD200 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD200 (CD200) (Active) protein (His tag)CD200 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD200 (CD200) (AA 31-232) protein (His tag)Crystallography grade CD200 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD200 (CD200) (AA 31-232) protein (His tag)Crystallography grade CD200 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
CD200 (CD200) (AA 31-278) protein (rho-1D4 tag)Crystallography grade CD200 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized from 0.2μm-filtered solution in PBS.
- 注意事项
- Avoid freeze/thaw cycles.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
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- 抗原
- CD200
- 别名
- CD200 (CD200 产品)
- 别名
- MOX1 Protein, MOX2 Protein, MRC Protein, OX-2 Protein, CD200 Protein, Cspmo2 Protein, MRCOX2 Protein, Mox2 Protein, DKFZp459C0716 Protein, OX2 Protein, CD200 molecule Protein, Cd200 molecule Protein, CD200 antigen Protein, CD200 Protein, Cd200 Protein
- 背景
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Alternate Names/Synonyms: OX-2 Membrane Glycoprotein, MOX2
Product Description: CD200, also known as OX-2, is a 45 kDa transmembrane immunoregulatory protein that belongs to the immunoglobulin superfamily. CD200 is widely but not ubiquitously expressed. Its receptor (CD200R) is restricted primarily to mast cells, basophils, macrophages, and dendritic cells, which suggests myeloid cell regulation as the major function of CD200. CD200 knockout mice are characterized by increased macrophage number and activation and are predisposed to autoimmune disorders. In T cells, CD200 functions as a costimulatory molecule independent of the CD28 pathway. Several viruses encode CD200 homologs which are expressed on infected cells during the lytic phase. Like CD200 itself, viral CD200 homologs also suppress myeloid cell activity, enabling increased viral propagation.
- NCBI登录号
- NP_034948
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