Neuroglobin Protein (NGB)
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- 抗原 See all Neuroglobin (NGB) 蛋白
- Neuroglobin (NGB)
- 蛋白类型
- Recombinant
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- 序列
- MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E.
- 特异性
- The amino acid sequence of the Neuroglobin human recombinant is 100% homologous to the amino acid sequence of the human Neuroglobin.
- 产品特性
- Recombinant Human Neuroglobin
- 纯化方法
- Two-step procedure using size exclusion chromatography before and after refolding.
- 纯度
- > 95 % as determined by SDS-PAGE.
- 过滤
- Sterile
- Top Product
- Discover our top product NGB 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Sterile filtered and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2.Add 0.2 ml of H2O and let the lyophilized pellet dissolve completely.
- 储存条件
- -20 °C
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- 抗原
- Neuroglobin (NGB)
- 别名
- Neuroglobin (NGB 产品)
- 别名
- NGB Protein, ngb Protein, neuroglobin Protein, neuroglobin L homeolog Protein, NGB Protein, Ngb Protein, ngb Protein, ngb.L Protein
- 背景
- 17kDa protein containing 151 amino acid residues of the Neuroglobin human Introduction: Neuroglobin, 151 amino acid residue protein, mainly expressed in vertebrate brain and retina, is a recently identified member of the globin superfamily. Augmenting O (2) supply, neuroglobin promotes survival of neurons upon hypoxic injury, potentially limiting brain damage. Moreover, neuroglobin may be a novel oxidative stress-responsive sensor for signal transduction in the brain. Neuroglobin expression is increased by neuronal hypoxia in vitro and focal cerebral ischemia in vivo, and neuronal survival after hypoxia is reduced by inhibiting neuroglobin expression with an antisense oligodeoxynucleotide and enhanced by neuroglobin overexpression. Synonyms: NGB.
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