CCL17 蛋白
(1 reference)-
- 抗原 See all CCL17 蛋白
- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
- 蛋白类型
- Recombinant
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宿主
- 人
- 宿主
- 请咨询
- 序列
- ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S.
- 产品特性
- Recombinant Human Thymus and Activation Regulated Chemokine (TARC) / CCL17
- 纯度
- > 97.0 % as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
- Top Product
- Discover our top product CCL17 蛋白
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Chemokine (C-C Motif) Ligand 17 (CCL17) (AA 24-93) protein (His tag)
CCL17 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 17 (CCL17) (AA 24-93) protein (His tag)CCL17 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 17 (CCL17) (AA 24-94) protein (GST tag)CCL17 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 17 (CCL17) (AA 1-740) protein (Strep Tag)Crystallography grade CCL17 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Chemokine (C-C Motif) Ligand 17 (CCL17) (AA 1-741) protein (Strep Tag)Crystallography grade CCL17 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- The protein was lyophilized from a concentrated (0.5mg/ml) solution containing 20mM PBS and 150mM NaCl pH-7.4.It is recommended to reconstitute the lyophilized CCL17 in sterile 18M omega cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
- 储存条件
- -20 °C
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: "Altered profile of chemokines in fibromyalgia patients." in: Annals of clinical biochemistry, Vol. 51, Issue Pt 5, pp. 576-81, (2014) (PubMed).
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: "Altered profile of chemokines in fibromyalgia patients." in: Annals of clinical biochemistry, Vol. 51, Issue Pt 5, pp. 576-81, (2014) (PubMed).
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- 抗原
- CCL17 (Chemokine (C-C Motif) Ligand 17 (CCL17))
- 别名
- Thymus and Activation Regulated Chemokine (TARC) / CCL17 (CCL17 产品)
- 别名
- A-152E5.3 Protein, ABCD-2 Protein, SCYA17 Protein, TARC Protein, CCL17 Protein, Abcd-2 Protein, Scya17 Protein, Scya17l Protein, Tarc Protein, abcd2 Protein, C-C motif chemokine ligand 17 Protein, chemokine (C-C motif) ligand 17 Protein, ATP-binding cassette sub-family D member 2 Protein, CCL17 Protein, Ccl17 Protein, LOC100537809 Protein
- 背景
- CCL17 Human Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 71 amino acids and having a molecular mass of 8 kDa. The TARC is purified by proprietary chromatographic techniques. Introduction: TARC cDNA encodes a 94 amino acid precursor protein with a 23 amino acid residue signal peptide that is cleaved off to generate the 71 amino acid residue mature secreted protein. Along with CC chemokine family members, CCL-17 has approximately 24-29% amino acid sequence identity with RANTES, MIP-1alpha, MIP-1beta, MCP-1, MCP-2, MCP-3 and I-309. TARC is expressed in thymus, and at a lower level in the lung, colon, and small intestine. TARC is in addition transiently expressed in stimulated peripheral blood mononuclear cells. Recombinant TARC has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL-17 was recently identified to be a specific functional ligand for CCR4, a receptor that is selectively expressed on T cells. CCL17 is one of quite a few Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. CCL17 shows chemotactic activity for T lymphocytes, but not monocytes or granulocytes. CCL17 binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. Synonyms: C-C motif chemokine 17, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CC chemokine TARC, ABCD-2, CCL17, CCL-17, SCYA17, TARC, A-152E5.3, MGC138271, MGC138273.
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