AATF Protein (AA 6-294, partial) (GST tag)
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- 抗原 See all AATF 蛋白
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- 蛋白类型
- Recombinant
- 产品特性
- AA 6-294, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This AATF protein is labelled with GST tag.
- 应用范围
- Western Blotting (WB), SDS-PAGE (SDS), ELISA
- 序列
- PLALQLEQLL NPRPSEADPE ADPEEATAAR VIDRFDEGED GEGDFLVVGS IRKLASASLL DTDKRYCGKT TSRKAWNEDH WEQTLPGSSD EEISDEEGSG DEDSEGLGLE EYDEDDLGAA EEQECGDHRE SKKSRSHSAK TPGFSVQSIS DFEKFTKGMD DLGSSEEEED EESGMEEGDD AEDSQGESEE DRAGDRNSED DGVVMTFSSV KVSEEVEKGR AVKNQIALWD QLLEGRIKLQ KALLTTNQLP QPDVFPLFKD KGGPEFSSAL KNSHKALKAL LRSLVGLQE
- 纯度
- 95 %
- Top Product
- Discover our top product AATF 蛋白
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Apoptosis Antagonizing Transcription Factor (AATF) (AA 151-250) protein (GST tag)
AATF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apoptosis Antagonizing Transcription Factor (AATF) (AA 1-560) protein (GST tag)AATF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Apoptosis Antagonizing Transcription Factor (AATF) (AA 2-560) protein (His tag)Crystallography grade AATF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Antagonizing Transcription Factor (AATF) (AA 2-526) protein (His tag)Crystallography grade AATF 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Antagonizing Transcription Factor (AATF) protein (DYKDDDDK Tag)AATF 宿主: 人 宿主: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Apoptosis Antagonizing Transcription Factor (AATF) proteinAATF 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % WB, SDS, ELISA, IP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS buffer, 20mM GSH
- 储存条件
- 4 °C
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- 抗原
- AATF (Apoptosis Antagonizing Transcription Factor (AATF))
- 别名
- Protein AATF (AATF 产品)
- 别名
- AATF Protein, ded Protein, che1 Protein, che-1 Protein, cb109 Protein, sb:cb109 Protein, wu:fc13d05 Protein, zgc:162071 Protein, CHE-1 Protein, CHE1 Protein, DED Protein, 4933415H02Rik Protein, 5830465M17Rik Protein, Che-1 Protein, Trb Protein, Ded Protein, apoptosis antagonizing transcription factor Protein, Apoptosis antagonizing transcription factor Protein, apoptosis antagonizing transcription factor S homeolog Protein, AATF Protein, aatf Protein, BFR2 Protein, NAEGRDRAFT_56916 Protein, Aatf Protein, aatf.S Protein
- 背景
- Background: May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date. Synonyms: Apoptosis-antagonizing transcription factor Rb-binding protein Che-1.
- 分子量
- 59.1 kD
- NCBI登录号
- NM_012138
- UniProt
- Q9NY61
- 途径
- Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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