N-Cadherin Protein (AA 160-724) (His tag)
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- 抗原 See all N-Cadherin (CDH2) 蛋白
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 160-724
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This N-Cadherin protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ADPDWVIPPI NLPENSRGPF PQELVRIRSD RDKNLSLRYS VTGPGADQPP TGIFIINPIS GQLSVTKPLD REQIARFHLR AHAVDINGNQ VENPIDIVIN VIDMNDNRPE FLHQVWNGTV PEGSKPGTYV MTVTAIDADD PNALNGMLRY RIVSQAPSTP SPNMFTINNE TGDIITVAAG LDREKVQQYT LIIQATDMEG NPTYGLSNTA TAVITVTDVN DNPPEFTAMT FYGEVPENRV DIIVANLTVT DKDQPHTPAW NAVYRISGGD PTGRFAIQTD PNSNDGLVTV VKPIDFETNR MFVLTVAAEN QVPLAKGIQH PPQSTATVSV TVIDVNENPY FAPNPKIIRQ EEGLHAGTML TTFTAQDPDR YMQQNIRYTK LSDPANWLKI DPVNGQITTI AVLDRESPNV KNNIYNATFL ASDNGIPPMS GTGTLQIYLL DINDNAPQVL PQEAETCETP DPNSINITAL DYDIDPNAGP FAFDLPLSPV TIKRNWTITR LNGDFAQLNL KIKFLEAGIY EVPIIITDSG NPPKSNISIL RVKVCQCDSN GDCTDVDRIV GAGLGTGAHH HHHH
- 纯度
- > 90 % by SDS - PAGE
- 内毒素水平
- < 1.0 EU per 1ug of protein (determined by LAL method)
- Top Product
- Discover our top product CDH2 蛋白
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Cadherin 2 (CDH2) (AA 160-724) protein (His-DYKDDDDK-Strep II Tag)
CDH2 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
Cadherin 2 (CDH2) (AA 773-906) protein (His-IF2DI Tag)CDH2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Cadherin 2 (CDH2) (AA 807-906) protein (GST tag)CDH2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 20 % glycerol.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- 别名
- CDH2 (CDH2 产品)
- 别名
- CD325 Protein, CDHN Protein, CDw325 Protein, NCAD Protein, N-cadherin Protein, cadherin-2 Protein, cdhn Protein, ncad Protein, cdw325 Protein, CDH2 Protein, Cadherin-2 Protein, Ncad Protein, glo Protein, lyr Protein, pac Protein, wu:fb47h04 Protein, cadherin 2 Protein, cadherin 2 S homeolog Protein, cadherin 2, type 1, N-cadherin (neuronal) Protein, CDH2 Protein, cdh2.S Protein, cdh2 Protein, Cdh2 Protein
- 背景
- CDH2, also known as cadherin-2 isoform 1, is a transmembrane, homophilic glycoprotein belonging to the calcium-dependent cell adhesion molecule family. It plays a role in neurons and later was found to also play a role in cardiac muscle and in cancer metastasis. Its loss promotes tumorigenesis by releasing membrane-bound B-catenin, hence stimulating Wnt signaling. It seems to be involved in tumor development, but this finding is limited in adrenocortical tumors (ACTs). Recombinant human CDH2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- 分子量
- 62.9kDa (574aa) 70-100kDa (SDS-PAGE under reducing conditions)
- NCBI登录号
- NP_001783
- UniProt
- P19022
- 途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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