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CD131 Protein (AA 17-443) (His tag)
CSF2RB
宿主: 人
宿主: Baculovirus infected Insect Cells
Recombinant
> 95 % by SDS - PAGE
SDS
产品细节
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抗原
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CD131 (CSF2RB)
(Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))
蛋白类型
Recombinant
产品特性
AA 17-443
宿主
All origins for CD131 蛋白
人
资源
All sources for CD131 蛋白
Baculovirus infected Insect Cells
标记
This CD131 protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
序列
WERSLAGAEE TIPLQTLRCY NDYTSHITCR WADTQDAQRL VNVTLIRRVN EDLLEPVSCD LSDDMPWSAC PHPRCVPRRC VIPCQSFVVT DVDYFSFQPD RPLGTRLTVT LTQHVQPPEP RDLQISTDQD HFLLTWSVAL GSPQSHWLSP GDLEFEVVYK RLQDSWEDAA ILLSNTSQAT LGPEHLMPSS TYVARVRTRL APGSRLSGRP SKWSPEVCWD SQPGDEAQPQ NLECFFDGAA VLSCSWEVRK EVASSVSFGL FYKPSPDAGE EECSPVLREG LGSLHTRHHC QIPVPDPATH GQYIVSVQPR RAEKHIKSSV NIQMAPPSLN VTKDGDSYSL RWETMKMRYE HIDHTFEIQY RKDTATWKDS KTETLQNAHS MALPALEPST RYWARVRVRT SRTGYNGIWS EWSEARSWDT ESVLPMWLEH HHHHH
纯度
> 95 % by SDS - PAGE
内毒素水平
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.5 mg/mL
缓冲液
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
CD131 (CSF2RB)
(Colony Stimulating Factor 2 Receptor, Beta (CSF2RB))
别名
Cytokine receptor common subunit beta (CSF2RB 产品 )
别名
Csf2rb1 Protein, CSF2RB Protein, cd131 Protein, cdw131 Protein, il3rb Protein, il5rb Protein, il-3rbc Protein, CD131 Protein, CDw131 Protein, IL3RB Protein, IL5RB Protein, SMDP5 Protein, AI848964 Protein, AIC2B Protein, Bc Protein, Csfgmrb Protein, Il3r Protein, Il3rb Protein, Il3rb1 Protein, Il5rb Protein, colony stimulating factor 2 receptor beta common subunit Protein, colony stimulating factor 2 receptor beta common subunit S homeolog Protein, cytokine receptor common subunit beta-like Protein, colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Protein, CSF2RB Protein, Csf2rb Protein, csf2rb.S Protein, CRCBL Protein, csf2rb Protein
背景
CSF2RB, also known as cytokine receptor common subunit beta, is a high affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. This unusual form of receptor assembly likely applies also to IL-3 and IL-5 receptors, providing a structural basis for understanding their mechanism of activation and for the development of therapeutics. Recombinant human CSF2RB, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
分子量
49.7kDa (435aa) 40-57kDa (SDS-PAGE under reducing conditions)
NCBI登录号
NP_000386
UniProt
P32927
途径
JAK/STAT Signaling
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CD131 蛋白
CD131 Protein (AA 17-443) (His tag) (ABIN5854442)