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PEBP1 Protein (AA 1-187) (His tag)

PEBP1 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS - PAGE SDS
产品编号 ABIN5854348
发货至: 中国
  • 抗原 See all PEBP1 蛋白
    PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-187
    宿主
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 6
    • 3
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This PEBP1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMAADISQ WAGPLCLQEV DEPPQHALRV DYAGVTVDEL GKVLTPTQVM NRPSSISWDG LDPGKLYTLV LTDPDAPSRK DPKFREWHHF LVVNMKGNDI SSGTVLSDYV GSGPPSGTGL HRYVWLVYEQ EQPLSCDEPI LSNKSGDNRG KFKVETFRKK YNLGAPVAGT CYQAEWDDYV PKLYEQLSGK
    纯度
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product PEBP1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
    别名
    Pebp1 (PEBP1 产品)
    别名
    HCNP Protein, HCNPpp Protein, PBP Protein, PEBP Protein, PEBP-1 Protein, RKIP Protein, pbp Protein, hcnp Protein, pebp Protein, rkip Protein, Pbp Protein, Pbp1 Protein, Pbpr Protein, Rkip Protein, PEBP1 Protein, BcDNA:LP12095 Protein, CG18594 Protein, Dmel\\CG18594 Protein, T2 Protein, zgc:56033 Protein, zgc:76942 Protein, phosphatidylethanolamine binding protein 1 Protein, phosphatidylethanolamine binding protein 1 L homeolog Protein, phosphatidylethanolamine-binding protein Protein, phosphatidylethanolamine-binding protein,putative Protein, Phosphatidylethanolamine-binding protein 1 Protein, PEBP1 Protein, pebp1 Protein, Pebp1 Protein, pebp1.L Protein, RR_RS07785 Protein, PVX_235290 Protein, PVX_123630 Protein, PKH_143640 Protein, EAM_1207 Protein
    背景
    Pebp1 also known as Phosphatidylethanolamine-binding protein 1. The protein Binds with ATP, opioids and phosphatidylethanolamine. Pebp1 exerts inhibitory activity against several serine proteases including thrombin, neuropsin, and chymotrypsin, it also inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation. Also, targeting Pebp1 levels can delay photoreceptor degeneration, assisting in extending the time-window for treating such rapidly progressing blindness disorder. Recombinant mouse Pebp1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    23.2kDa (210aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_061346
    UniProt
    P70296
    途径
    Feeding Behaviour
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