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PRKAA1 Protein (AA 1-279) (His tag)
PRKAA1
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
> 85 % by SDS - PAGE
SDS
产品细节
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抗原
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PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
蛋白类型
Recombinant
产品特性
AA 1-279
宿主
All origins for PRKAA1 蛋白
人
资源
All sources for PRKAA1 蛋白
大肠杆菌(E. Coli)
标记
This PRKAA1 protein is labelled with His tag.
应用范围
SDS-PAGE (SDS)
序列
MGSSHHHHHH SSGLVPRGSH MGSMRRLSSW RKMATAEKQK HDGRVKIGHY ILGDTLGVGT FGKVKVGKHE LTGHKVAVKI LNRQKIRSLD VVGKIRREIQ NLKLFRHPHI IKLYQVISTP SDIFMVMEYV SGGELFDYIC KNGRLDEKES RRLFQQILSG VDYCHRHMVV HRDLKPENVL LDAHMNAKIA DFGLSNMMSD GEFLRTSCGS PNYAAPEVIS GRLYAGPEVD IWSSGVILYA LLCGTLPFDD DHVPTLFKKI CDGIFYTPQY LNPSVISLLK HMLQVDPMKR ATIKDIREHE WF
纯度
> 85 % by SDS - PAGE
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
1 mg/mL
缓冲液
Liquid, In 20 mM Tris-HCl buffer( pH 8.0) containing 10 % glycerol
储存条件
4 °C,-20 °C,-80 °C
储存方法
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
目标详细情况
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抗原
PRKAA1
(Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))
别名
PRKAA,1 (PRKAA1 产品 )
别名
AMPK Protein, AMPKa1 Protein, cb116 Protein, im:7154392 Protein, sb:cb130 Protein, wu:fa94c10 Protein, AMPK1 Protein, AMPKalpha1 Protein, AI194361 Protein, AI450832 Protein, AL024255 Protein, C130083N04Rik Protein, ampk Protein, ampka1 Protein, PRKAA1 Protein, protein kinase AMP-activated catalytic subunit alpha 1 Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit Protein, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog Protein, PRKAA1 Protein, prkaa1 Protein, Prkaa1 Protein, prkaa1.L Protein
背景
PRKAA1 also known as 5-AMP-activated protein kinase catalytic subunit alpha-1 isoform 1. PRKAA1 is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinasen activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Recombinant human PRKAA1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
分子量
34.3kDa (302aa)
NCBI登录号
NP_006242
UniProt
Q13131
途径
AMPK Signaling , Carbohydrate Homeostasis , Regulation of Carbohydrate Metabolic Process , Warburg Effect
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