DPY30 Protein (AA 1-99) (His tag)
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- 抗原 See all DPY30 蛋白
- DPY30 (Dpy-30 Homolog (DPY30))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-99
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This DPY30 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMEPEQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVD LQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN
- 纯度
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product DPY30 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 30 % glycerol, 2 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- DPY30 (Dpy-30 Homolog (DPY30))
- 别名
- DPY30 (DPY30 产品)
- 别名
- HDPY-30 Protein, Saf19 Protein, 2810410M20Rik Protein, C87842 Protein, Aip1 Protein, dpy-30, histone methyltransferase complex regulatory subunit Protein, dpy-30 histone methyltransferase complex regulatory subunit Protein, DPY30 Protein, Dpy30 Protein
- 背景
- As part of the MLL1/MLL complex, DPY30 is involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. This protein may play some role in histone H3 acetylation. In a teratocarcinoma cell, it plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. DPY30 may also play an indirect or direct role in endosomal transport. Recombinant human DPY30 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 13.6 kDa (122aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_115963
- UniProt
- Q9C005
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