IYD Protein (AA 24-214) (His tag)
IYD
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
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- 抗原 See all IYD 蛋白
- IYD (Iodotyrosine Deiodinase (IYD))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-214
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IYD protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSDRSMEKK KGEPRTRAEA RPWVDEDLKD SSDLHQAEED ADEWQESEEN VEHIPFSHNH YPEKEMVKRS QEFYELLNKR RSVRFISNEQ VPMEVIDNVI RTAGTAPSGA HTEPWTFVVV KDPDVKHKIR KIIEEEEEIN YMKRMGHRWV TDLKKLRTNW IKEYLDTAPI LILIFKQVHG FAANGKKKVH YYNE
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product IYD 蛋白
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Iodotyrosine Deiodinase (IYD) (AA 1-289) protein (GST tag)
IYD 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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Denatured
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M uREA, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- IYD (Iodotyrosine Deiodinase (IYD))
- 别名
- IYD (IYD 产品)
- 别名
- MGC85450 Protein, C6orf71 Protein, DEHAL1 Protein, TDH4 Protein, dJ422F24.1 Protein, 0610009A07Rik Protein, AI265638 Protein, Dehal1 Protein, RGD1309288 Protein, IYD-1 Protein, iodotyrosine deiodinase Protein, iodotyrosine deiodinase L homeolog Protein, IYD Protein, iyd.L Protein, iyd Protein, Iyd Protein
- 背景
- IYD is an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. Recombinant human IYD protein, fused to His-tag at N-terminus, was expressed in E.coli.
- 分子量
- 25.1kDa (214aa)
- NCBI登录号
- NP_001158167
- UniProt
- Q6PHW0
- 途径
- Thyroid Hormone Synthesis
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