SNURF Protein (AA 1-71) (His tag)
SNURF
宿主: 人
宿主: 大肠杆菌（E. Coli）
Recombinant
> 90 % by SDS - PAGE
SDS
1 image
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- 抗原 See all SNURF 蛋白
- SNURF (SNRPN Upstream Reading Frame (SNURF))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-71
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This SNURF protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMERARDR LHLRRTTEQH VPEVEVQVKR RRTASLSNQE CQLYPRRSQQ QQVPVVDFQA ELRQAFLAET PRGG
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product SNURF 蛋白
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SNRPN Upstream Reading Frame (SNURF) (AA 1-71) protein (His tag)
SNURF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 40 % glycerol, 1 mM DTT.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- SNURF (SNRPN Upstream Reading Frame (SNURF))
- 别名
- SNuRF (SNURF 产品)
- 别名
- 2410045I01Rik Protein, Snrpn Protein, SNRPN upstream reading frame Protein, small nuclear ribonucleoprotein polypeptide N Protein, SNURF Protein, SNRPN Protein, Snurf Protein
- 背景
- SNuRF is a highly basic protein localized to the nucleus. The evolutionarily constrained open reading frame is found on a bicistronic transcript which has a downstream ORF encoding the small nuclear ribonucleoprotein polypeptide N. The upstream coding region utilizes the first three exons of the transcript, a region that has been identified as an imprinting center. Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region but the full-length nature of these transcripts has not been determined. An alternate exon has been identified that substitutes for exon 4 and leads to a truncated, monocistronic transcript. Alternative splicing or deletion caused by a translocation event in the 5' uTR or coding region of this gene leads to Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure. The function of this protein is not yet known. Recombinant human SNuRF protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 10.8 kDa (94aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_073715
- UniProt
- Q9Y675
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