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ARPP19 Protein (AA 1-112) (His tag)

ARPP19 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN5853398
发货至: 中国
  • 抗原 See all ARPP19 蛋白
    ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))
    蛋白类型
    Recombinant
    产品特性
    AA 1-112
    宿主
    • 3
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    资源
    • 5
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    大肠杆菌(E. Coli)
    标记
    This ARPP19 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMSAEVPE AASAEEQKEM EDKVTSPEKA EEAKLKARYP HLGQKPGGSD FLRKRLQKGQ KYFDSGDYNM AKAKMKNKQL PTAAPDKTEV TGDHIPTPQD LPQRKPSLVA SKLAG
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product ARPP19 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 10 % glycerol
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))
    别名
    ARPP19 (ARPP19 产品)
    别名
    ARPP-16 Protein, ARPP-19 Protein, ARPP16 Protein, ENSAL Protein, ARPP-19-A Protein, arpp-16 Protein, arpp-19 Protein, arpp16 Protein, arpp19-a Protein, ensal Protein, 19kDa Protein, 2700024H10Rik Protein, AW559096 Protein, Arpp12 Protein, Arpp19 Protein, Arpp-19 Protein, cAMP regulated phosphoprotein 19 Protein, cAMP regulated phosphoprotein 19kDa L homeolog Protein, cAMP-regulated phosphoprotein 19 Protein, ARPP19 Protein, arpp19.L Protein, Arpp19 Protein
    背景
    CAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GAP-43 expression. Recombinant human ARPP19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    14.7kDa (135aa) confirmed by MALDI-TOF
    NCBI登录号
    NP_006619
    UniProt
    P56211
    途径
    Regulation of Carbohydrate Metabolic Process
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