ARPP19 Protein (AA 1-112) (His tag)
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- 抗原 See all ARPP19 蛋白
- ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-112
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This ARPP19 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMSAEVPE AASAEEQKEM EDKVTSPEKA EEAKLKARYP HLGQKPGGSD FLRKRLQKGQ KYFDSGDYNM AKAKMKNKQL PTAAPDKTEV TGDHIPTPQD LPQRKPSLVA SKLAG
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ARPP19 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- ARPP19 (cAMP-Regulated Phosphoprotein, 19kDa (ARPP19))
- 别名
- ARPP19 (ARPP19 产品)
- 别名
- ARPP-16 Protein, ARPP-19 Protein, ARPP16 Protein, ENSAL Protein, ARPP-19-A Protein, arpp-16 Protein, arpp-19 Protein, arpp16 Protein, arpp19-a Protein, ensal Protein, 19kDa Protein, 2700024H10Rik Protein, AW559096 Protein, Arpp12 Protein, Arpp19 Protein, Arpp-19 Protein, cAMP regulated phosphoprotein 19 Protein, cAMP regulated phosphoprotein 19kDa L homeolog Protein, cAMP-regulated phosphoprotein 19 Protein, ARPP19 Protein, arpp19.L Protein, Arpp19 Protein
- 背景
- CAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GAP-43 expression. Recombinant human ARPP19 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- 分子量
- 14.7kDa (135aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_006619
- UniProt
- P56211
- 途径
- Regulation of Carbohydrate Metabolic Process
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