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Dynamitin Protein (AA 1-401) (His tag)

DCTN2 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN5853385
发货至: 中国
  • 抗原 See all Dynamitin (DCTN2) 蛋白
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    蛋白类型
    Recombinant
    产品特性
    AA 1-401
    宿主
    • 6
    • 1
    • 1
    • 1
    • 1
    资源
    • 4
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This Dynamitin protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMADPKYA DLPGIARNEP DVYETSDLPE DDQAEFDAEE LTSTSVEHII VNPNAAYDKF KDKRVGTKGL DFSDRIGKTK RTGYESGEYE MLGEGLGVKE TPQQKYQRLL HEVQELTTEV EKIKTTVKES ATEEKLTPVL LAKQLAALKQ QLVASHLEKL LGPDAAINLT DPDGALAKRL LLQLEATKNS KGGSGGKTTG TPPDSSLVTY ELHSRPEQDK FSQAAKVAEL EKRLTELETA VRCDQDAQNP LSAGLQGACL METVELLQAK VSALDLAVLD QVEARLQSVL GKVNEIAKHK ASVEDADTQS KVHQLYETIQ RWSPIASTLP ELVQRLVTIK QLHEQAMQFG QLLTHLDTTQ QMIANSLKDN TTLLTQVQTT MRENLATVEG NFASIDERMK KLGK
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product DCTN2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl(  pH 8.0) containing 20 % glycerol, 0.15M NaCl, 1  mM DTT
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    别名
    DCTN2 (DCTN2 产品)
    别名
    DCTN2 Protein, dctn2 Protein, dctn50 Protein, dynamitin Protein, rbp50 Protein, CG8269 Protein, DMN Protein, Dmel\\CG8269 Protein, P50 Protein, dDyn Protein, dmn Protein, dyna Protein, l(2)k16109 Protein, l(2)k16218 Protein, p50 Protein, p50/Dmn Protein, p50/dynamitin Protein, 2310042E05Rik Protein, C130077D06Rik Protein, C87049 Protein, DCTN-50 Protein, GMP23-48K Protein, RBP50 Protein, DCTN50 Protein, DYNAMITIN Protein, zgc:63867 Protein, dynactin subunit 2 Protein, dynactin subunit 2 S homeolog Protein, Dynactin 2, p50 subunit Protein, dynactin 2 Protein, dynactin 2 (p50) Protein, dynactin subunit 2 L homeolog Protein, DCTN2 Protein, dctn2.S Protein, DCTN2-p50 Protein, dctn2 Protein, Dctn2 Protein, dctn2.L Protein
    背景
    DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Recombinant human DCTN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    46.6kDa (424aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_001248342
    UniProt
    Q13561
    途径
    M Phase, Ribonucleoprotein Complex Subunit Organization
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