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TRIAP1 Protein (AA 1-76) (His tag)

TRIAP1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN5853375
发货至: 中国
  • 抗原 See all TRIAP1 蛋白
    TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-76
    宿主
    • 2
    • 1
    • 1
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This TRIAP1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSMNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TRIAP1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.1M NaCl, 20 % glycerol, 1  mM DTT
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))
    别名
    TRIAP1 (TRIAP1 产品)
    别名
    MDM35 Protein, P53CSV Protein, WF-1 Protein, 1810015M01Rik Protein, AU020874 Protein, AU043831 Protein, P53csv Protein, Wf-1 Protein, p53csv-A Protein, triap1 Protein, triap1a Protein, p53csv-B Protein, triap1-a Protein, triap1-b Protein, triap1b Protein, zgc:112025 Protein, TP53 regulated inhibitor of apoptosis 1 Protein, TP53 regulated inhibitor of apoptosis 1 S homeolog Protein, TP53 regulated inhibitor of apoptosis 1 L homeolog Protein, TRIAP1 Protein, Triap1 Protein, triap1.S Protein, triap1.L Protein, triap1 Protein
    背景
    TP53-regulated inhibitor of apoptosis 1, also known as TRIAP1, contains a p53-binding site within its second exon and the reduction of expression by small interfering RNA enhanced apoptosis, whereas overexpression protected cells from apoptosis caused by DNA damage. TRIAP1 is induced significantly when cells have a low level of genotoxic stresses, but not when DNA damage is severe. TRIAP1 can modulate apoptotic pathways through interaction with Hsp70 that probably inhibits activity of apoptosis protease activating factor-1. Recombinant human TRIAP1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    11.2kDa (99aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_057483
    UniProt
    O43715
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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