CT4.2 Protein, GAGE-2 Protein, GAGE-2A Protein, GAGE2 Protein, G antigen 2A Protein, GAGE2A Protein
背景
GAGE2A belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells. Recombinant human GAGE2A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
分子量
15 kDa (139aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)