RNF7 Protein (AA 1-113) (His tag)
-
- 抗原 See all RNF7 蛋白
- RNF7 (Ring Finger Protein 7 (RNF7))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-113
- 宿主
- 人
-
资源
- 大肠杆菌(E. Coli)
- 标记
- This RNF7 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSMADVEDG EETCALASHS GSSGSKSGGD KMFSLKKWNA VAMWSWDVEC DTCAICRVQV MDACLRCQAE NKQEDCVVVW GECNHSFHNC CMSLWVKQNN RCPLCQQDWV VQRIGK
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RNF7 蛋白
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
-
Denatured
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.0 mg/mL
- 缓冲液
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
-
- 抗原
- RNF7 (Ring Finger Protein 7 (RNF7))
- 别名
- RNF7 (RNF7 产品)
- 别名
- CKBBP1 Protein, ROC2 Protein, SAG Protein, Rbx2 Protein, ring finger protein 7 Protein, RNF7 Protein, Rnf7 Protein
- 背景
- RNF7 is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHuK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. Recombinant human RNF7 protein, fused to His-tag at N-terminus, was expressed in E.coli .
- 分子量
- 15.1 kDa (136aa)
- NCBI登录号
- NP_055060
- UniProt
- Q9UBF6
- 途径
- Positive Regulation of Endopeptidase Activity
-