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MPZL1 Protein (AA 38-162) (His tag)

MPZL1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN5853109
发货至: 中国
  • 抗原 See all MPZL1 蛋白
    MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
    蛋白类型
    Recombinant
    产品特性
    AA 38-162
    宿主
    • 6
    • 2
    • 1
    资源
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This MPZL1 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MGSSHHHHHH SSGLVPRGSH MGSLEVYTPK EIFVANGTQG KLTCKFKSTS TTGGLTSVSW SFQPEGADTT VSFFHYSQGQ VYLGNYPPFK DRISWAGDLD KKDASINIEN MQFIHNGTYI CDVKNPPDIV VQPGHIRLYV VEKENLPV
    纯度
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product MPZL1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.15M NaCl, 20 % glycerol, 1  mM DTT
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
    别名
    MPZL1 (MPZL1 产品)
    别名
    MPZL1 Protein, MPZL1b Protein, PZR Protein, PZR1b Protein, PZRa Protein, PZRb Protein, 1110007A10Rik Protein, myelin protein zero like 1 Protein, myelin protein zero-like 1 Protein, MPZL1 Protein, Mpzl1 Protein
    背景
    MPZL1 is a cell surface receptor, which is involved in signal transduction processes. This protein recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility. Recombinant human MPZL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    分子量
    16.1 kDa (148aa), confirmed by MALDI-TOF
    NCBI登录号
    NP_078845
    UniProt
    O95297
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