-
- 抗原
- DYST (Dystocia (Maternal) (DYST))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-195, partial
- 宿主
- 人
- 资源
- 酵母菌
- 标记
- This DYST protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MHSSSYSYRS SDSVFSNTTS TRTSLDSNEN LLLVHCGPTL INSCISFGSE SFDGHRLEML QQIANRVQRD SVICEDKLIL AGNALQSDSK RLESGVQFQN EAEIAGYILE CENLLRQHVI DVQILIDGKY YQADQLVQRV AKLRDEIMAL RNECSSVYSK GRILTTEQTK LMISGITQSL NSGFAQTLHP SLTSG
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- 抗原
- DYST (Dystocia (Maternal) (DYST))
- 别名
- DYST
- 背景
- Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh.Isoform 3: plays a structural role in the assbly of hidesmosomes of epithelial cells, anchors keratin-containing intermediate filaments to the inner plaque of hidesmosomes. Required for the regulation of keratinocyte polarity and motility, mediates integrin ITGB4 regulation of RAC1 activity.Isoform 6: required for bundling actin filaments around the nucleus.Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
- 分子量
- 23.7 kDa
- UniProt
- Q03001
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