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CD163 Protein (CD163) (AA 86-365, partial) (His tag)

CD163 宿主: 小鼠 宿主: 酵母菌 Recombinant > 90 % SDS
产品编号 ABIN5714360
发货至: 中国
  • 抗原 See all CD163 蛋白
    CD163
    蛋白类型
    Recombinant
    产品特性
    partial, AA 86-365
    宿主
    • 12
    • 6
    • 2
    小鼠
    资源
    • 9
    • 5
    • 4
    • 1
    酵母菌
    标记
    This CD163 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    VVCQQLGCPT SIKALGWANS SAGSGYIWMD KVSCTGNESA LWDCKHDGWG KHNCTHEKDA GVTCSDGSNL EMRLVNSAGH RCLGRVEIKF QGKWGTVCDD NFSKDHASVI CKQLGCGSAI SFSGSAKLGA GSGPIWLDDL ACNGNESALW DCKHRGWGKH NCDHAEDVGV ICLEGADLSL RLVDGVSRCS GRLEVRFQGE WGTVCDDNWD LRDASVVCKQ LGCPTAISAI GRVNASEGSG QIWLDNISCE GHEATLWECK HQEWGKHYCH HREDAGVTCS
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product CD163 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    CD163
    别名
    C163A (CD163 产品)
    别名
    DMBT1 Protein, CD163 Protein, CD163v2 Protein, CD163v3 Protein, M130 Protein, MM130 Protein, deleted in malignant brain tumors 1 protein-like Protein, CD163 molecule Protein, CD163 antigen Protein, LOC426820 Protein, CD163 Protein, Cd163 Protein
    背景
    Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 .After shedding, the soluble form (sCD163) may play an anti-inflammatory role.
    分子量
    32.2 kDa
    UniProt
    Q2VLH6
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