CD163 Protein (CD163) (AA 86-365, partial) (His tag)
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- 抗原 See all CD163 蛋白
- CD163
- 蛋白类型
- Recombinant
- 产品特性
- partial, AA 86-365
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宿主
- 小鼠
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资源
- 酵母菌
- 标记
- This CD163 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- VVCQQLGCPT SIKALGWANS SAGSGYIWMD KVSCTGNESA LWDCKHDGWG KHNCTHEKDA GVTCSDGSNL EMRLVNSAGH RCLGRVEIKF QGKWGTVCDD NFSKDHASVI CKQLGCGSAI SFSGSAKLGA GSGPIWLDDL ACNGNESALW DCKHRGWGKH NCDHAEDVGV ICLEGADLSL RLVDGVSRCS GRLEVRFQGE WGTVCDDNWD LRDASVVCKQ LGCPTAISAI GRVNASEGSG QIWLDNISCE GHEATLWECK HQEWGKHYCH HREDAGVTCS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product CD163 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- CD163
- 别名
- C163A (CD163 产品)
- 别名
- DMBT1 Protein, CD163 Protein, CD163v2 Protein, CD163v3 Protein, M130 Protein, MM130 Protein, deleted in malignant brain tumors 1 protein-like Protein, CD163 molecule Protein, CD163 antigen Protein, LOC426820 Protein, CD163 Protein, Cd163 Protein
- 背景
- Involved in clearance and endocytosis of hoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hoglobin/haptoglobin and subsequent breakdown of he. Binds hoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 .After shedding, the soluble form (sCD163) may play an anti-inflammatory role.
- 分子量
- 32.2 kDa
- UniProt
- Q2VLH6
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