hCoV-OC43 Spike Protein (AA 15-344, partial) (His tag)
(1 reference)-
- 抗原 See all hCoV-OC43 Spike (HCoV-OC43 S) products
- hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))
- 蛋白类型
- Recombinant
- 产品特性
- partial, AA 15-344
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宿主
- Human Coronavirus OC43 (HCoV-OC43)
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资源
- 酵母菌
- 标记
- This hCoV-OC43 Spike protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- VIGDLKCTSD NINDKDTGPP PISTDTVDVT NGLGTYYVLD RVYLNTTLFL NGYYPTSGST YRNMALKGSV LLSRLWFKPP FLSDFINGIF AKVKNTKVIK DRVMYSEFPA ITIGSTFVNT SYSVVVQPRT INSTQDGDNK LQGLLEVSVC QYNMCEYPQT ICHPNLGNHR KELWHLDTGV VSCLYKRNFT YDVNADYLYF HFYQEGGTFY AYFTDTGVVT KFLFNVYLGM ALSHYYVMPL TCNSKLTLEY WVTPLTSRQY LLAFNQDGII FNAEDCMSDF MSEIKCKTQS IAPPTGVYEL NGYTVQPIAD VYRRKPNLPN CNIEAWLNDK
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
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Coronavirus OC43 Spike Protein (HCoV-OC43 S) protein (His tag)
HCoV-OC43 S 宿主: Human Coronavirus OC43 (HCoV-OC43) 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE.
Coronavirus OC43 Spike Protein (HCoV-OC43 S) protein (His tag,ECD)HCoV-OC43 S 宿主: Human Coronavirus OC43 (HCoV-OC43) 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by reducing SDS-PAGE.
Coronavirus OC43 Spike Protein (HCoV-OC43 S) (AA 15-344), (partial) protein (His-SUMO Tag)HCoV-OC43 S 宿主: Human Coronavirus OC43 (HCoV-OC43) 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).
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: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).
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- 抗原
- hCoV-OC43 Spike (HCoV-OC43 S) (Coronavirus OC43 Spike Protein (HCoV-OC43 S))
- 别名
- OC43 Spike Glycoprotein (HCoV-OC43 S 产品)
- 物质类
- Viral Protein
- 背景
- S1 attaches the virion to the cell mbrane by interacting with sialic acid-containing cell receptors, initiating the infection.S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell mbrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell mbranes.
- 分子量
- 39.6 kDa
- UniProt
- P36334
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