MICAL2 Protein (AA 1-495, partial) (His tag)
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- 抗原 See all MICAL2 蛋白
- MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-495, partial
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宿主
- 人
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资源
- 酵母菌
- 标记
- This MICAL2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGENEDEKQA QAGQVFENFV QASTCKGTLQ AFNILTRHLD LDPLDHRNFY SKLKSKVTTW KAKALWYKLD KRGSHKEYKR GKSCTNTKCL IVGGGPCGLR TAIELAYLGA KVVVVEKRDS FSRNNVLHLW PFTIHDLRGL GAKKFYGKFC AGSIDHISIR QLQLILFKVA LMLGVEIHVN VEFVKVLEPP EDQENQKIGW RAEFLPTDHS LSEFEFDVII GADGRRNTLE GFRRKEFRGK LAIAITANFI NRNSTAEAKV EEISGVAFIF NQKFFQDLKE ETGIDLENIV YYKDCTHYFV MTAKKQSLLD KGVIINDYID TEMLLCAENV NQDNLLSYAR EAADFATNYQ LPSLDFAMNH YGQPDVAMFD FTCMYASENA ALVRERQAHQ LLVALVGDSL LEPFWPMGTG CARGFLAAFD TAWMVKSWNQ GTPPLELLAE RESLYRLLPQ TTPENINKNF EQYTLDPGTR YPNLNSHCVR PHQVKHLYIT KELEH
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product MICAL2 蛋白
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Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2) (AA 1021-1123) protein (GST tag)
MICAL2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2) (AA 1-1124) protein (His tag)Crystallography grade MICAL2 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2) (AA 1-960) protein (His tag)Crystallography grade MICAL2 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))
- 别名
- MICA2 (MICAL2 产品)
- 别名
- MICAL-2 Protein, MICAL2PV1 Protein, MICAL2PV2 Protein, 5330438E18Rik Protein, 9530064J02 Protein, mKIAA0750 Protein, RGD1311773 Protein, microtubule associated monooxygenase, calponin and LIM domain containing 2 Protein, MICAL2 Protein, Mical2 Protein
- 背景
- Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.
- 分子量
- 58.48 kDa
- UniProt
- O94851
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