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- 抗原 See all GBA 蛋白
- GBA (Glucosidase, Beta, Acid (GBA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 53-89
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宿主
- 人
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资源
- 酵母菌
- 标记
- This GBA protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- HSQGTFTSDY SKYLDSRRAQ DFVQWLMNTK RNRNNIA
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product GBA 蛋白
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Glucosidase, Beta, Acid (GBA) (AA 362-512) protein (His-IF2DI Tag)
GBA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Glucosidase, Beta, Acid (GBA) (AA 1-536) protein (GST tag)GBA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glucosidase, Beta, Acid (GBA) (AA 146-235) protein (GST tag)GBA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glucosidase, Beta, Acid (GBA) (AA 431-536) protein (GST tag)GBA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Glucosidase, Beta, Acid (GBA) (AA 20-515) protein (His tag)Crystallography grade GBA 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Glucosidase, Beta, Acid (GBA) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)GBA 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- GBA (Glucosidase, Beta, Acid (GBA))
- 别名
- GLUC (GBA 产品)
- 别名
- GBA1 Protein, GCB Protein, GLUC Protein, BETA-GLUCOSIDASE Protein, T12J13.8 Protein, T12J13_8 Protein, beta glucosidase 25 Protein, PSPTO3318 Protein, PSPTO4290 Protein, GC Protein, GCase Protein, betaGC Protein, glucosylceramidase beta Protein, beta glucosidase 25 Protein, beta-glucosidase Protein, Beta-glucosidase Protein, glucosidase, beta, acid Protein, glucosylceramidase Protein, bglX-2 Protein, GBA Protein, BGLU25 Protein, PSPTO_3318 Protein, bglX Protein, bglA4 Protein, Gba Protein, LOC100399524 Protein, bglA.2 Protein, bglX-2 Protein
- 背景
- Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycia. Plays an important role in initiating and maintaining hyperglycic conditions in diabetes.GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis.GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability.Oxyntomodulin significantly reduces food intake. Inhibits gastric ptying in humans. Suppression of gastric ptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness.Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.
- 分子量
- 6.4 kDa
- UniProt
- P01275
- 途径
- Cellular Glucan Metabolic Process
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