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ESR2 Protein (AA 2-530) (His tag)

ESR2 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
产品编号 ABIN5713440
发货至: 中国
  • 抗原 See all ESR2 蛋白
    ESR2 (Estrogen Receptor 2 (ESR2))
    蛋白类型
    Recombinant
    产品特性
    AA 2-530
    宿主
    • 7
    • 3
    • 2
    • 1
    • 1
    资源
    • 7
    • 2
    • 2
    • 2
    • 1
    酵母菌
    标记
    This ESR2 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    DIKNSPSSLN SPSSYNCSQS ILPLEHGSIY IPSSYVDSHH EYPAMTFYSP AVMNYSIPSN VTNLEGGPGR QTTSPNVLWP TPGHLSPLVV HRQLSHLYAE PQKSPWCEAR SLEHTLPVNR ETLKRKVSGN RCASPVTGPG SKRDAHFCAV CSDYASGYHY GVWSCEGCKA FFKRSIQGHN DYICPATNQC TIDKNRRKSC QACRLRKCYE VGMVKCGSRR ERCGYRLVRR QRSADEQLHC AGKAKRSGGH APRVRELLLD ALSPEQLVLT LLEAEPPHVL ISRPSAPFTE ASMMMSLTKL ADKELVHMIS WAKKIPGFVE LSLFDQVRLL ESCWMEVLMM GLMWRSIDHP GKLIFAPDLV LDRDEGKCVE GILEIFDMLL ATTSRFRELK LQHKEYLCVK AMILLNSSMY PLVTATQDAD SSRKLAHLLN AVTDALVWVI AKSGISSQQQ SMRLANLLML LSHVRHASNK GMEHLLNMKC KNVVPVYDLL LEMLNAHVLR GCKSSITGSE CSPAEDSKSK EGSQNPQSQ
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product ESR2 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    ESR2 (Estrogen Receptor 2 (ESR2))
    别名
    ESR2 (ESR2 产品)
    别名
    ER-BETA Protein, ESR-BETA Protein, ESRB Protein, ESTRB Protein, Erb Protein, NR3A2 Protein, ER[b]1 Protein, zfER-beta1 Protein, zfER[b]1 Protein, erb2 Protein, CERB Protein, ERB Protein, erb Protein, esrb Protein, estrb Protein, nr3a2 Protein, ERbeta Protein, er-beta Protein, esr-beta Protein, ESR2 Protein, ERBETA Protein, er Protein, ER-beta Protein, ER[b] Protein, Estrb Protein, ER[b]2 Protein, ER[b]a Protein, zfER[b]2 Protein, zfER-beta2 Protein, Erb2 Protein, esr2 Protein, erbeta Protein, Esr2 Protein, ERBeta2 Protein, estrogen receptor 2 Protein, estrogen receptor 2b Protein, estrogen receptor beta 2 Protein, estrogen receptor 2 (beta) Protein, estrogen receptor 2a Protein, estrogen receptor beta Protein, ESR2 Protein, esr2b Protein, erb2 Protein, esr2 Protein, Esr2 Protein, esr2a Protein, erbeta Protein
    背景
    Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elents (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated tperature is more gradual.
    分子量
    60 kDa
    UniProt
    Q92731
    途径
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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