eIF4EBP2 Protein (AA 1-120, full length) (His tag)
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- 抗原 See all eIF4EBP2 (EIF4EBP2) 蛋白
- eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-120
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宿主
- 人
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资源
- 酵母菌
- 标记
- This eIF4EBP2 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MSSSAGSGHQ PSQSRAIPTR TVAISDAAQL PHDYCTTPGG TLFSTTPGGT RIIYDRKFLL DRRNSPMAQT PPCHLPNIPG VTSPGTLIED SKVEVNNLNN LNNHDRKHAV GDDAQFEMDI
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product EIF4EBP2 蛋白
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Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 1-120) protein (His tag)
EIF4EBP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 61-120) protein (GST tag)EIF4EBP2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 1-120) protein (GST tag)EIF4EBP2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 1-120), (full length) protein (GST tag)EIF4EBP2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) (AA 1-120), (full length) protein (His tag)EIF4EBP2 宿主: 人 宿主: 酵母菌 Recombinant > 90 % SDS
Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2) protein (Myc-DYKDDDDK Tag)EIF4EBP2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- eIF4EBP2 (EIF4EBP2) (Eukaryotic Translation Initiation Factor 4E Binding Protein 2 (EIF4EBP2))
- 别名
- 4EBP2 (EIF4EBP2 产品)
- 别名
- 4ebp2 Protein, MGC75579 Protein, wu:fa55e11 Protein, wu:fp45e09 Protein, MGC78987 Protein, EIF4EBP2 Protein, eIF-4E Protein, Tb06.28P18.1010 Protein, 4EBP2 Protein, PHASII Protein, 2810011I19Rik Protein, 4E-BP2 Protein, AA792569 Protein, BC010348 Protein, PHAS-II Protein, eukaryotic translation initiation factor 4E binding protein 2 Protein, eukaryotic translation initiation factor 4E binding protein 2 L homeolog Protein, eukaryotic initiation factor 4E Protein, eukaryotic translation initiation factor 4E Protein, putative eukaryotic translation initiation factor 4e Protein, eif4ebp2 Protein, Eif4ebp2 Protein, eif4ebp2.L Protein, EIF4EBP2 Protein, eIF-4E Protein, Tb927.6.1870 Protein, LMJF_30_0450 Protein
- 背景
- Repressor of translation initiation involved in synaptic plasticity, learning and mory formation . Regulates EIF4E activity by preventing its assbly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation . EIF4EBP2 is enriched in brain and acts as a regulator of synapse activity and neuronal st cell renewal via its ability to repress translation initiation . Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways .
- 分子量
- 14.9 kDa
- UniProt
- Q13542
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