MMP13 Protein (AA 105-472) (His tag)
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- 抗原 See all MMP13 蛋白
- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
- 蛋白类型
- Recombinant
- 产品特性
- AA 105-472
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MMP13 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- YNVFPRTLKW SQTNLTYRIV NYTPDMSHSE VEKAFRKAFK VWSDVTPLNF TRIYDGTADI MISFGTKEHG DFYPFDGPSG LLAHAFPPGP NYGGDAHFDD DETWTSSSKG YNLFIVAAHE LGHSLGLDHS KDPGALMFPI YTYTGKSHFM LPDDDVQGIQ FLYGPGDEDP NPKHPKTPEK CDPALSLDAI TSLRGETMIF KDRFFWRLHP QQVEAELFLT KSFWPELPNH VDAAYEHPSR DLMFIFRGRK FWALNGYDIL EGYPRKISDL GFPKEVKRLS AAVHFENTGK TLFFSENHVW SYDDVNQTMD KDYPRLIEEE FPGIGNKVDA VYEKNGYIYF FNGPIQFEYS IWSNRIVRVM PTNSILWC
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product MMP13 蛋白
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Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 104-274) protein (His tag)
MMP13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 266-471) protein (His-IF2DI Tag)MMP13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 362-471) protein (GST tag)MMP13 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 104-471) protein (His tag)Crystallography grade MMP13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 105-472) protein (His tag)Crystallography grade MMP13 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
- 别名
- MMP13 (MMP13 产品)
- 别名
- CLG3 Protein, MANDP1 Protein, Clg Protein, MMP-13 Protein, Mmp1 Protein, cb1034 Protein, mmp13 Protein, gene A Protein, xCol Protein, xcl3 Protein, MMP13 Protein, MGC108008 Protein, matrix metallopeptidase 13 Protein, matrix metallopeptidase 13a Protein, matrix metallopeptidase 13 (collagenase 3) like S homeolog Protein, matrix metallopeptidase 13 (collagenase 3) Protein, matrix metalloproteinase 13 Protein, matrix metallopeptidase 13 (collagenase 3) like L homeolog Protein, MMP13 Protein, Mmp13 Protein, mmp13a Protein, mmp13l.S Protein, mmp13 Protein, LOC100136348 Protein, mmp13l.L Protein
- 背景
- Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue rodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal bryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
- 分子量
- 46.5 kDa
- UniProt
- P33435
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