TR4 Protein (AA 3-592, partial) (His tag)
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- 抗原 See all TR4 (NR2C2) 蛋白
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 3-592, partial
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TR4 protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- SPSPRIQIIS TDSAVASPQR IQIVTDQQTG QKIQIVTAVD ASGSPKQQFI LTSPDGAGTG KVILASPETS SAKQLIFTTS DNLVPGRIQI VTDSASVERL LGKTDVQRPQ VVEYCVVCGD KASGRHYGAV SCEGCKGFFK RSVRKNLTYS CRSNQDCIIN KHHRNRCQFC RLKKCLEMGM KMESVQSERK PFDVQREKPS NCAASTEKIY IRKDLRSPLI ATPTFVADKD GARQTGLLDP GMLVNIQQPL IREDGTVLLA TDSKAETSQG ALGTLANVVT SLANLSESLN NGDTSEIQPE DQSASEITRA FDTLAKALNT TDSSSSPSLA DGIDTSGGGS IHVISRDQST PIIEVEGPLL SDTHVTFKLT MPSPMPEYLN VHYICESASR LLFLSMHWAR SIPAFQALGQ DCNTSLVRAC WNELFTLGLA QCAQVMSLST ILAAIVNHLQ NSIQEDKLSG DRIKQVMEHI WKLQEFCNSM AKLDIDGYEY AYLKAIVLFS PDHPGLTSTS QIEKFQEKAQ MELQDYVQKT YSEDTYRLAR ILVRLPALRL MSSNITEELF FTGLIGNVSI DSIIPYILKM ETAEYNGQIT
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product NR2C2 蛋白
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Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 43-152) protein (GST tag)
NR2C2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-530) protein (GST tag)NR2C2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-596) protein (Strep Tag)Crystallography grade NR2C2 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) (AA 1-596) protein (Strep Tag)Crystallography grade NR2C2 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2) protein (Myc-DYKDDDDK Tag)NR2C2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TR4 (NR2C2) (Nuclear Receptor Subfamily 2, Group C, Member 2 (NR2C2))
- 别名
- NR2C2 (NR2C2 产品)
- 别名
- TAK1 Protein, TR2R1 Protein, TR4 Protein, hTAK1 Protein, Tr4 Protein, gb:dq017625 Protein, im:6911408 Protein, mKIAA4145 Protein, nuclear receptor subfamily 2 group C member 2 Protein, nuclear receptor subfamily 2, group C, member 2 Protein, NR2C2 Protein, Nr2c2 Protein, nr2c2 Protein
- 背景
- Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear recptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during expression during the late phase of spermatogenesis. Activates transcriptional activity of LHCG and is antagonist of PPARA-mediated transactivation . Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses bryonic and fetal globin transcription including that of GATA1. Binds to hormone response elents (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early bryonic development and bryonic st cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior
- 分子量
- 68.9 kDa
- UniProt
- P49117
- 途径
- TCR Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades
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