ANG Protein (AA 24-148) (His tag)
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- 抗原 See all ANG 蛋白
- ANG (Angiogenin (ANG))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-148
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宿主
- Cow
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资源
- 大肠杆菌(E. Coli)
- 标记
- This ANG protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- AQDDYRYIHF LTQHYDAKPK GRNDEYCFNM MKNRRLTRPC KDRNTFIHGN KNDIKAICED RNGQPYRGDL RISKSEFQIT ICKHKGGSSR PPCRYGATED SRVIVVGCEN GLPVHFDESF ITPRH
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product ANG 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- ANG (Angiogenin (ANG))
- 别名
- ANG1 (ANG 产品)
- 别名
- ALS9 Protein, HEL168 Protein, RNASE4 Protein, RNASE5 Protein, ANG Protein, AI385586 Protein, Ang1 Protein, Rnase5 Protein, Rnase5a Protein, ANG1 Protein, angiogenin Protein, angiogenin, ribonuclease, RNase A family, 5 Protein, ribonuclease A family member k6 Protein, ANG Protein, Ang Protein, RNASE6 Protein
- 背景
- Binds to actin on the surface of endothelial cells, once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assbly of stress granules (SGs) . Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity.
- 分子量
- 18.7 kDa
- UniProt
- P10152
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