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- 抗原 See all UBE2K 蛋白
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-200
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This UBE2K protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ANIAVQRIKR EFKEVLKSEE TSKNQIKVDL VDENFTELRG EIAGPPDTPY EGGRYQLEIK IPETYPFNPP KVRFITKIWH PNISSVTGAI CLDILKDQWA AAMTLRTVLL SLQALLAAAE PDDPQDAVVA NQYKQNPEMF KQTARLWAHV YAGAPVSSPE YTKKIENLCA MGFDRNAVIV ALSSKSWDVE TATELLLSN
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product UBE2K 蛋白
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Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (His tag)
UBE2K 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (AA 1-200) protein (GST tag)UBE2K 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Transcript Variant 3) protein (His tag)UBE2K 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2K (UBE2K) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2K 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))
- 别名
- UBE2K (UBE2K 产品)
- 别名
- E2-25K Protein, HIP2 Protein, HYPG Protein, LIG Protein, UBC1 Protein, E2-25k Protein, Hip2 Protein, Hypg Protein, Lig Protein, e2-25k Protein, hip2 Protein, hypg Protein, lig Protein, AW492011 Protein, D5Ertd601e Protein, ube2k Protein, zgc:103472 Protein, zgc:110791 Protein, ubiquitin conjugating enzyme E2 K Protein, ubiquitin-conjugating enzyme E2K Protein, ubiquitin conjugating enzyme E2 K S homeolog Protein, ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) Protein, ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) Protein, UBE2K Protein, Ube2k Protein, ube2k.S Protein, ube2k Protein, ube2kb Protein, ube2ka Protein
- 背景
- Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B, in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1
- 分子量
- 26.4 kDa
- UniProt
- P61086
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