Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
抗原
DRAP1
(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
fb26e10 Protein, zgc:56003 Protein, zgc:77337 Protein, wu:fb26e10 Protein, DRAP1 Protein, 2310074H19Rik Protein, NC2-alpha Protein, DR1-associated protein 1 (negative cofactor 2 alpha) Protein, DR1 associated protein 1 Protein, Dr1 associated protein 1 (negative cofactor 2 alpha) Protein, Dr1 associated protein 1 Protein, drap1 Protein, DRAP1 Protein, Drap1 Protein
背景
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.