HNRNPK Protein (AA 3-459, partial) (GST tag)
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- 抗原 See all HNRNPK 蛋白
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- 蛋白类型
- Recombinant
- 产品特性
- AA 3-459, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This HNRNPK protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- TEQPEETFPN TETNGEFGKR PAEDMEEEQA FKRSRNTDEM VELRILLQSK NAGAVIGKGG KNIKALRTDY NASVSVPDSS GPERILSISA DIETIGEILK KIIPTLEEGL QLPSPTATSQ LPLESDAVEC LNYQHYKGSD FDCELRLLIH QSLAGGIIGV KGAKIKELRE NTQTTIKLFQ ECCPHSTDRV VLIGGKPDRV VECIKIILDL ISESPIKGRA QPYDPNFYDE TYDYGGFTMM FDDRRGRPVG FPMRGRGGFD RMPPGRGGRP MPPSRRDYDD MSPRRGPPPP PPGRGGRGGS RARNLPLPPP PPPRGGDLMA YDRRGRPGDR YDGMVGFSAD ETWDSAIDTW SPSEWQMAYE PQGGSGYDYS YAGGRGSYGD LGGPIITTQV TIPKDLAGSI IGKGGQRIKQ IRHESGASIK IDEPLEGSED RIITITGTQD QIQNAQYLLQ NSVKQYADVE GF
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product HNRNPK 蛋白
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Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) protein (GST tag)
HNRNPK 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 3-459), (partial) protein (GST tag)HNRNPK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)HNRNPK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-276) protein (His tag)HNRNPK 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HNRNPK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)HNRNPK 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- 别名
- HNRPK (HNRNPK 产品)
- 别名
- CSBP Protein, HNRPK Protein, TUNP Protein, Csbp Protein, Hnrpk Protein, hnrpk Protein, MGC75642 Protein, wu:fb37h02 Protein, wu:fi34c04 Protein, zgc:66162 Protein, KBBP Protein, NOVA Protein, heterogeneous nuclear ribonucleoprotein K Protein, heterogeneous nuclear ribonucleoprotein K S homeolog Protein, heterogeneous nuclear ribonucleoprotein k Protein, HNRNPK Protein, Hnrnpk Protein, hnrnpk.S Protein, hnrnpk Protein, LOC5565718 Protein, CpipJ_CPIJ000130 Protein, NGK_p0004 Protein
- 背景
- One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction . As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.3 Publications
- 分子量
- 78.1 kDa
- UniProt
- P61978
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