Sorting Nexin 3 Protein (SNX3) (AA 3-162) (GST tag)
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- 抗原 See all Sorting Nexin 3 (SNX3) 蛋白
- Sorting Nexin 3 (SNX3)
- 蛋白类型
- Recombinant
- 产品特性
- AA 3-162
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Sorting Nexin 3 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- ETVADTRRLI TKPQNLNDAY GPPSNFLEID VSNPQTVGVG RGRFTTYEIR VKTNLPIFKL KESTVRRRYS DFEWLRSELE RESKVVVPPL PGKAFLRQLP FRGDDGIFDD NFIEERKQGL EQFINKVAGH PLAQNERCLH MFLQDEIIDK SYTPSKIRHA
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product SNX3 蛋白
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Sorting Nexin 3 (SNX3) (AA 1-162) protein (His tag)
SNX3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Sorting Nexin 3 (SNX3) (AA 1-113) protein (GST tag)SNX3 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Sorting Nexin 3 (SNX3) (AA 3-162), (full length) protein (GST tag)SNX3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % ELISA
Sorting Nexin 3 (SNX3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SNX3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- Sorting Nexin 3 (SNX3)
- 别名
- SNX3 (SNX3 产品)
- 别名
- SNX3 Protein, sdp3 Protein, Grd19 Protein, snx3a Protein, wu:fb53a08 Protein, zgc:123189 Protein, MCOPS8 Protein, SDP3 Protein, sorting nexin 3 Protein, sorting nexin 3 L homeolog Protein, potential phosphoinositide-binding protein similar to S. cerevisiae GRD19 (YOR357C) late Golgi protein involved in retrieval of proteins from prevacuolar compartment; same as cosmid orf Ca41C10.03 Protein, SNX3 Protein, snx3.L Protein, snx3 Protein, GRD19 Protein, Snx3 Protein
- 背景
- Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2) . Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome mbrane association of the retromer cargo-selective subcomplex (CSC/VPS). May in part act as component of the SNX3-retromer complex which mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway . Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G . Not involved in EGFR degradation. Involved in the regulation of phagocytosis in dendritic cells possibly by regulating EEA1 recruitment to the nascent phagosomes . Involved in iron homeostasis through regulation of endocytic recycling of the transferrin receptor TFRC presumably by delivering the tranferrin:transferrin receptor complex to recycling endosomes, the function may involve the CSC retromer subcomplex . In the case of Salmonella enterica infection plays arole in maturation of the Salmonella-containing vacuole (SCV) and promotes recruitment of LAMP1 to SCVs .
- 分子量
- 45.9 kDa
- UniProt
- O60493
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