DYNLL1 Protein (AA 1-89, full length) (GST tag)
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- 抗原 See all DYNLL1 蛋白
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-89
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DYNLL1 protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product DYNLL1 蛋白
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Dynein, Light Chain, LC8-Type 1 (DYNLL1) (AA 1-89) protein (His tag)
DYNLL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (AA 1-89) protein (GST tag)DYNLL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (AA 1-72) protein (GST tag)DYNLL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (AA 1-89) protein (Strep Tag)Crystallography grade DYNLL1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (Transcript Variant 1) protein (His tag)DYNLL1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)DYNLL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)DYNLL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Dynein, Light Chain, LC8-Type 1 (DYNLL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)DYNLL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- 别名
- DYL1 (DYNLL1 产品)
- 别名
- DLC1 Protein, DLC8 Protein, DNCL1 Protein, DNCLC1 Protein, LC8 Protein, LC8a Protein, PIN Protein, hdlc1 Protein, dynll2 Protein, wu:fd56c09 Protein, zgc:73406 Protein, Dlc8 Protein, Dnclc1 Protein, Pin Protein, 8kDLC Protein, lc8 Protein, dlc1 Protein, dlc8 Protein, lc8a Protein, dncl1 Protein, dnclc1 Protein, dynll1a Protein, MGC68763 Protein, CDLC2 Protein, dynll1 Protein, dynll1b Protein, pin Protein, MGC89636 Protein, dynein light chain LC8-type 1 Protein, dynein, light chain, LC8-type 1 Protein, dynein light chain LC8-type 1 S homeolog Protein, dynein light chain LC8-type 1 L homeolog Protein, Dynein light chain 1, cytoplasmic Protein, DYNLL1 Protein, dynll1 Protein, Dynll1 Protein, dynll1.S Protein, dynll1.L Protein, dlc-1 Protein
- 背景
- Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.Binds and inhibits the catalytic activity of neuronal nitric oxide synthase.Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1.Regulates apoptotic activities of BCL2L11 by sequestering it to microtubules. Upon apoptotic stimuli the BCL2L11-DYNLL1 complex dissociates from cytoplasmic dynein and translocates to mitochondria and sequesters BCL2 thus neutralizing its antiapoptotic activity.
- 分子量
- 37.8 kDa
- UniProt
- P63167
- 途径
- M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity
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