MBNL1 Protein (AA 1-382) (His-SUMO Tag)
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- 抗原 See all MBNL1 蛋白
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-382
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This MBNL1 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MAVSVTPIRD TKWLTLEVCR EFQRGTCSRP DTECKFAHPS KSCQVENGRV IACFDSLKGR CSRENCKYLH PPPHLKTQLE INGRNNLIQQ KNMAMLAQQM QLANAMMPGA PLQPVPMFSV APSLATNASA AAFNPYLGPV SPSLVPAEIL PTAPMLVTGN PGVPVPAAAA AAAQKLMRTD RLEVCREYQR GNCNRGENDC RFAHPADSTM IDTNDNTVTV CMDYIKGRCS REKCKYFHPP AHLQAKIKAA QYQVNQAAAA QAAATAAAMG IPQAVLPPLP KRPALEKTNG ATAVFNTGIF QYQQALANMQ LQQHTAFLPP GSILCMTPAT SVVPMVHGAT PATVSAATTS ATSVPFAATA TANQIPIISA EHLTSHKYVT QM
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product MBNL1 蛋白
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Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 6) (Active) protein (Myc-DYKDDDDK Tag)
MBNL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Muscleblind-like Protein 1 (MBNL1) (AA 1-343) protein (GST tag)MBNL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Muscleblind-like Protein 1 (MBNL1) (AA 1-382) protein (GST tag)MBNL1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Muscleblind-like Protein 1 (MBNL1) (AA 1-388) protein (Strep Tag)Crystallography grade MBNL1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Muscleblind-like Protein 1 (MBNL1) (AA 1-341) protein (Strep Tag)Crystallography grade MBNL1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)MBNL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)MBNL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 5) protein (Myc-DYKDDDDK Tag)MBNL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Muscleblind-like Protein 1 (MBNL1) (Transcript Variant 7) protein (Myc-DYKDDDDK Tag)MBNL1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- MBNL1 (Muscleblind-like Protein 1 (MBNL1))
- 别名
- MBNL1 (MBNL1 产品)
- 别名
- MBNL1 Protein, zgc:153954 Protein, Mbnl Protein, mKIAA0428 Protein, EXP Protein, EXP35 Protein, EXP40 Protein, EXP42 Protein, MBNL Protein, muscleblind like splicing regulator 1 Protein, muscleblind-like splicing regulator 1 Protein, muscleblind like splicing factor 1 Protein, MBNL1 Protein, mbnl1 Protein, Mbnl1 Protein
- 背景
- Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the st-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assbly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues.
- 分子量
- 57 kDa
- UniProt
- Q9NR56
- 途径
- Ribonucleoprotein Complex Subunit Organization
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