CHMP5 Protein (AA 1-219, full length) (His-SUMO Tag)
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- 抗原 See all CHMP5 蛋白
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-219
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CHMP5 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MNRLFGKAKP KAPPPSLTDC IGTVDSRAES IDKKISRLDA ELVKYKDQIK KMREGPAKNM VKQKALRVLK QKRMYEQQRD NLAQQSFNME QANYTIQSLK DTKTTVDAMK LGVKEMKKAY KQVKIDQIED LQDQLEDMME DANEIQEALS RSYGTPELDE DDLEAELDAL GDELLADEDS SYLDEAASAP AIPEGVPTDT KNKDGVLVDE FGLPQIPAS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product CHMP5 蛋白
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Charged Multivesicular Body Protein 5 (CHMP5) (AA 1-219) protein (His tag)
CHMP5 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Charged Multivesicular Body Protein 5 (CHMP5) (AA 1-219) protein (GST tag)CHMP5 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Charged Multivesicular Body Protein 5 (CHMP5) (AA 1-219) protein (Strep Tag)Crystallography grade CHMP5 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Charged Multivesicular Body Protein 5 (CHMP5) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)CHMP5 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))
- 别名
- CHMP5 (CHMP5 产品)
- 别名
- SNF7DC2 Protein, cgi-34 Protein, hspc177 Protein, pnas-2 Protein, vps60 Protein, chmp5 Protein, zgc:64125 Protein, C9orf83 Protein, HSPC177 Protein, PNAS-2 Protein, Vps60 Protein, 2210412K09Rik Protein, AW545668 Protein, RGD1305968 Protein, charged multivesicular body protein 5 S homeolog Protein, charged multivesicular body protein 5b Protein, charged multivesicular body protein 5 Protein, charged multivesicular body protein 5 L homeolog Protein, chromatin modifying protein 5 Protein, chmp5.S Protein, chmp5b Protein, CHMP5 Protein, chmp5.L Protein, chmp5 Protein, Chmp5 Protein
- 背景
- Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting mbrane of the endosome and mostly are delivered to lysosomes enabling degradation of mbrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating mbrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent mbrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or mbrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.
- 分子量
- 40.6 kDa
- UniProt
- Q9NZZ3
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