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CPEB1 Protein (AA 1-486, full length) (His-SUMO Tag)

CPEB1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5711755
发货至: 中国
  • 抗原 See all CPEB1 蛋白
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    蛋白类型
    Recombinant
    产品特性
    AA 1-486, full length
    宿主
    • 7
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This CPEB1 protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    MLFPTSAQES SRGLPDANDL CLGLQSLSLT GWDRPWSTQD SDSSAQSSTH SVLSMLHNPL GNVLGKPPLS FLPLDPLGSD LVDKFPAPSV RGSRLDTRPI LDSRSSSPSD SDTSGFSSGS DHLSDLISSL RISPPLPFLS LSGGGPRDPL KMGVGSRMDQ EQAALAAVTP SPTSASKRWP GASVWPSWDL LEAPKDPFSI EREARLHRQA AAVNEATCTW SGQLPPRNYK NPIYSCKVFL GGVPWDITEA GLVNTFRVFG SLSVEWPGKD GKHPRCPPKG YVYLVFELEK SVRSLLQACS HDPLSPDGLS EYYFKMSSRR MRCKEVQVIP WVLADSNFVR SPSQRLDPSR TVFVGALHGM LNAEALAAIL NDLFGGVVYA GIDTDKHKYP IGSGRVTFNN QRSYLKAVSA AFVEIKTTKF TKKVQIDPYL EDSLCHICSS QPGPFFCRDQ VCFKYFCRSC WHWRHSMEGL RHHSPLMRNQ KNRDSS
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product CPEB1 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    别名
    CPEB1 (CPEB1 产品)
    别名
    CEBP Protein, CPE-BP1 Protein, CPEB Protein, AU024112 Protein, Cpeb Protein, mCPEB Protein, CPEB1 Protein, cpeb1 Protein, ZOR-1 Protein, cepb1b Protein, fd15c06 Protein, wu:fd15c06 Protein, zorba Protein, cytoplasmic polyadenylation element binding protein 1 Protein, hypothetical protein Protein, cytoplasmic polyadenylation element binding protein 1 L homeolog Protein, cytoplasmic polyadenylation element binding protein 1b Protein, cytoplasmic polyadenylation element binding protein 1 S homeolog Protein, CPEB1 Protein, Cpeb1 Protein, cpeb1 Protein, LOAG_17395 Protein, cpeb1.L Protein, cpeb1b Protein, cpeb1.S Protein
    背景
    Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation elent (CPE), an uridine-rich sequence elent (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation . Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses . Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation . Induces the assbly of stress granules in the absence of stress.
    分子量
    69.6 kDa
    UniProt
    Q9BZB8
    途径
    Synaptic Membrane
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