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HSD17B10 Protein (AA 2-261) (His-SUMO Tag)

HSD17B10 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5711745
发货至: 中国
  • 抗原 See all HSD17B10 蛋白
    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
    蛋白类型
    Recombinant
    产品特性
    AA 2-261
    宿主
    • 8
    • 2
    • 1
    • 1
    资源
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This HSD17B10 protein is labelled with His-SUMO Tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    AAACRSVKGL VAVITGGASG LGLATAERLV GQGASAVLLD LPNSGGEAQA KKLGNNCVFA PADVTSEKDV QTALALAKGK FGRVDVAVNC AGIAVASKTY NLKKGQTHTL EDFQRVLDVN LMGTFNVIRL VAGEMGQNEP DQGGQRGVII NTASVAAFEG QVGQAAYSAS KGGIVGMTLP IARDLAPIGI RVMTIAPGLF GTPLLTSLPE KVCNFLASQV PFPSRLGDPA EYAHLVQAII ENPFLNGEVI RLDGAIRMQP
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
    Top Product
    Discover our top product HSD17B10 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
    别名
    HCD2 (HSD17B10 产品)
    别名
    hadh2 Protein, im:6899159 Protein, wu:fj61f03 Protein, zgc:101605 Protein, abad Protein, camr Protein, erab Protein, hcd2 Protein, hsd10 Protein, mhbd Protein, mrpp2 Protein, mrx17 Protein, mrx31 Protein, mrxs10 Protein, schad Protein, sdr5c1 Protein, HADH2 Protein, HSD17B10 Protein, 17b-HSD10 Protein, ABAD Protein, CAMR Protein, DUPXp11.22 Protein, ERAB Protein, HCD2 Protein, MHBD Protein, MRPP2 Protein, MRX17 Protein, MRX31 Protein, MRXS10 Protein, SCHAD Protein, SDR5C1 Protein, 17bHSD10 Protein, Ads9 Protein, Hadh2 Protein, hydroxysteroid (17-beta) dehydrogenase 10 Protein, hydroxysteroid 17-beta dehydrogenase 10 Protein, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog Protein, HSD17B10 Protein, hsd17b10 Protein, hsd17b10.L Protein, Hsd17b10 Protein
    背景
    Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
    分子量
    42.8 kDa
    UniProt
    Q99714
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