TMEM66 Protein (AA 195-339) (His-SUMO Tag)
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- 抗原 See all TMEM66 蛋白
- TMEM66 (Transmembrane Protein 66 (TMEM66))
- 蛋白类型
- Recombinant
- 产品特性
- AA 195-339
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TMEM66 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- SDGQYSPPPY SEYPPFSHRY QRFTNSAGPP PPGFKSEFTG PQNTGHGATS GFGSAFTGQQ GYENSGPGFW TGLGTGGILG YLFGSNRAAT PFSDSWYYPS YPPSYPGTWN RAYSPLHGGS GSYSVCSNSD TKTRTASGYG GTRRR
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TMEM66 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TMEM66 (Transmembrane Protein 66 (TMEM66))
- 别名
- SARAF (TMEM66 产品)
- 别名
- FOAP-7 Protein, SARAF Protein, XTP3 Protein, 1810045K07Rik Protein, tmem66 Protein, Tmem66 Protein, TMEM66 Protein, store-operated calcium entry associated regulatory factor Protein, store-operated calcium entry-associated regulatory factor Protein, store-operated calcium entry-associated regulatory factor S homeolog Protein, transmembrane protein 66 Protein, SARAF Protein, Saraf Protein, saraf Protein, saraf.S Protein, MCYG_05410 Protein, MGYG_06464 Protein, Tsp_10089 Protein
- 背景
- Negative regulator of store-operated Ca2+ entry (SOCE) involved in protecting cells from Ca2+ overfilling. In response to cytosolic Ca2+ elevation after endoplasmic reticulum Ca2+ refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca2+ levels, and thus preventing the overload of the cell with excessive Ca2+ ions.
- 分子量
- 31.48 kDa
- UniProt
- Q96BY9
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