CHCHD4 Protein (AA 1-142, full length) (His-SUMO Tag)
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- 抗原 See all CHCHD4 蛋白
- CHCHD4 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-142
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CHCHD4 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MSYCRQEGKD RIIFVTKEDH ETPSSAELVA DDPNDPYEEH GLILPNGNIN WNCPCLGGMA SGPCGEQFKS AFSCFHYSTE EIKGSDCVDQ FRAMQECMQK YPDLYPQEDE DEEEEREKKP AEQAEETAPI EATATKEEEG SS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product CHCHD4 蛋白
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Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4) (AA 1-142) protein (GST tag)
CHCHD4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4) (AA 1-142) protein (Strep Tag)Crystallography grade CHCHD4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4) (AA 1-139) protein (Strep Tag)Crystallography grade CHCHD4 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CHCHD4 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- CHCHD4 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 4 (CHCHD4))
- 别名
- MIA40 (CHCHD4 产品)
- 别名
- 2410012P20Rik Protein, 2810014D17Rik Protein, AI838740 Protein, MIA40 Protein, TIMM40 Protein, mia40 Protein, timm40 Protein, chchd4 Protein, chchd4a Protein, fc10g04 Protein, wu:fc10g04 Protein, zgc:100849 Protein, si:dkey-202e22.1 Protein, chchd4b Protein, CaO19.2977 Protein, coiled-coil-helix-coiled-coil-helix domain containing 4 Protein, coiled-coil-helix-coiled-coil-helix domain containing 4 L homeolog Protein, coiled-coil-helix-coiled-coil-helix domain containing 4a Protein, coiled-coil-helix-coiled-coil-helix domain containing 4 S homeolog Protein, Mia40p Protein, Chchd4 Protein, CHCHD4 Protein, chchd4 Protein, chchd4.L Protein, chchd4a Protein, chchd4.S Protein, LOC100361898 Protein, MIA40 Protein
- 背景
- Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermbrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay syst.
- 分子量
- 32 kDa
- UniProt
- Q8N4Q1
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