Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
4921501M07 Protein, AL450317.13gm1 Protein, AW107703 Protein, CD20R Protein, D9Mgc41 Protein, D9Mgc48e Protein, ET2 Protein, zgc:63548 Protein, Cep63-A Protein, Cep63-B Protein, Xcep63 Protein, centrosomal protein 63 Protein, centrosomal protein 63kDa Protein, centrosomal protein 63kDa L homeolog Protein, CEP63 Protein, SYO3AOP1_1060 Protein, Cep63 Protein, cep63 Protein, cep63.L Protein
背景
Required for normal spindle assbly. Plays a key role in mother-centriole-dependent centriole duplication, through centrosomal recruitment of CEP152. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks (DSBs), is roved from centrosomes, this leads to the inactivation of spindle assbly and delay in mitotic progression.