DCUN1D1 Protein (AA 1-259, full length) (His-SUMO Tag)
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- 抗原 See all DCUN1D1 蛋白
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- 蛋白类型
- Recombinant
- 产品特性
- full length, AA 1-259
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This DCUN1D1 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product DCUN1D1 蛋白
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Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (His tag)
DCUN1D1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (GST tag)DCUN1D1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-89) protein (GST tag)DCUN1D1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) (AA 1-259) protein (Strep Tag)Crystallography grade DCUN1D1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1) protein (Myc-DYKDDDDK Tag)DCUN1D1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- DCUN1D1 (Defective in Cullin Neddylation 1, Domain Containing 1 (DCUN1D1))
- 别名
- DCNL1 (DCUN1D1 产品)
- 别名
- fd19a01 Protein, zgc:66414 Protein, wu:fd19a01 Protein, dcun1l1 Protein, rp42 Protein, sccro Protein, scro Protein, tes3 Protein, DCNL1 Protein, DCUN1L1 Protein, RP42 Protein, SCCRO Protein, SCRO Protein, Tes3 Protein, Rp42 Protein, pTes3 Protein, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) Protein, DCN1-like protein 1 Protein, DCN1, defective in cullin neddylation 1, domain containing 1 L homeolog Protein, defective in cullin neddylation 1 domain containing 1 Protein, dcun1d1 Protein, dcnl1 Protein, dcun1d1.L Protein, DCUN1D1 Protein, Dcun1d1 Protein
- 背景
- Part of an E3 ubiquitin ligase complex for neddylation. Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes. Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates . Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assbly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression .1 Publication
- 分子量
- 46.1 kDa
- UniProt
- Q96GG9
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