Crystallography grade
DENND1A
宿主: 小鼠
宿主: Tobacco (Nicotiana tabacum)
Recombinant
≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
SDS, ELISA, WB
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Liquid
浓度
0.1-2 mg/mL
缓冲液
20 mM Tris-HCl based buffer, pH 8.0
储存条件
-80 °C,4 °C,-20 °C
储存方法
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
RGD1307927 Protein, FAM31A Protein, KIAA1608 Protein, RP11-230L22.3 Protein, 6030446I19Rik Protein, connecdenn Protein, fam31a Protein, DENN domain containing 1A Protein, DENN/MADD domain containing 1A Protein, DENN domain-containing protein 1A Protein, DENN domain containing 1A S homeolog Protein, Dennd1a Protein, DENND1A Protein, dennd1a Protein, LOC100512328 Protein, dennd1a.S Protein
背景
Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles.