TEAD4 Protein (AA 74-434, partial) (His-SUMO Tag)
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- 抗原 See all TEAD4 蛋白
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
- 蛋白类型
- Recombinant
- 产品特性
- AA 74-434, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This TEAD4 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MYGRNELIAR YIKLRTGKTR TRKQVSSHIQ VLARRKAREI QAKLKDQAAK DKALQSMAAM SSAQIISATA FHSSMALARG PGRPAVSGFW QGALPGQAGT SHDVKPFSQQ TYAVQPPLPL PGFESPAGPA PSPSAPPAPP WQGRSVASSK LWMLEFSAFL EQQQDPDTYN KHLFVHIGQS SPSYSDPYLE AVDIRQIYDK FPEKKGGLKD LFERGPSNAF FLVKFWADLN TNIEDEGSSF YGVSSQYESP ENMIITCSTK VCSFGKQVVE KVETEYARYE NGHYSYRIHR SPLCEYMINF IHKLKHLPEK YMMNSVLENF TILQVVTNRD TQETLLCIAY VFEVSASEHG AQHHIYRLVK E
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TEAD4 蛋白
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TEA Domain Family Member 4 (TEAD4) (AA 151-260) protein (GST tag)
TEAD4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
TEA Domain Family Member 4 (TEAD4) (AA 74-434) protein (His tag)TEAD4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
TEA Domain Family Member 4 (TEAD4) (AA 1-361) protein (GST tag)TEAD4 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
TEA Domain Family Member 4 (TEAD4) (AA 1-434) protein (Strep Tag)Crystallography grade TEAD4 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
TEA Domain Family Member 4 (TEAD4) (AA 2-427) protein (His tag)Crystallography grade TEAD4 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TEAD4 (TEA Domain Family Member 4 (TEAD4))
- 别名
- TEAD4 (TEAD4 产品)
- 别名
- TEAD4 Protein, rtef1 Protein, tef-3 Protein, eftr-2 Protein, tefr-1 Protein, tcf13l1 Protein, hrtef-1b Protein, xdtef-1 Protein, xlDTEF-1 Protein, RTEF-1 Protein, TEF-1 Protein, TEF-3 Protein, EFTR-2 Protein, RTEF1 Protein, TCF13L1 Protein, TEF3 Protein, TEFR-1 Protein, hRTEF-1B Protein, ETFR-2 Protein, Etfr2 Protein, FR-19 Protein, TEAD-4 Protein, Tcf13r1 Protein, Tef3 Protein, Tefr Protein, Tefr1 Protein, Tefr1a Protein, TEA domain transcription factor 4 Protein, TEA domain transcription factor 4 S homeolog Protein, TEA domain family member 4 Protein, TEAD4 Protein, tead4 Protein, tead4.S Protein, Tead4 Protein
- 背景
- Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
- 分子量
- 56.6 kDa
- UniProt
- Q15561
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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