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NCAP (AA 1-498), (full length) protein (His tag)

宿主: Influenza A Virus H3N2 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS
产品编号 ABIN5711219
发货至: 中国
  • 抗原
    NCAP
    蛋白类型
    Recombinant
    产品特性
    AA 1-498, full length
    宿主
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Influenza A Virus H3N2
    资源
    • 6
    • 3
    大肠杆菌(E. Coli)
    标记
    His tag
    应用范围
    SDS-PAGE (SDS)
    序列
    MASQGTKRSY EQMETDGERQ NATEIRASVG KMIDGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDERRNRYLE EHPSAGKDPK KTGGPIYKRV DGRWMRELVL YDKEEIRRIW RQANNGDDAT AGLTHMMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGIGTMV MELIRMIKRG INDRNFWRGE NGRKTRSAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFSA RSALILRGSV AHKSCLPACV YGPAVSSGYN FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACHSAAFED LRLLSFIRGT KVSPRGKLST RGVQIASNEN MDNMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISVQP TFSVQRNLPF EKSTVMAAFT GNTEGRTSDM RAEIIRMMEG AKPEEVSFRG RGVFELSDEK ATNPIVPSFD MSNEGSYFFG DNAEEYDN
    纯化方法
    SDS-PAGE
    纯度
    > 90 %
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.1-2 mg/mL
    缓冲液
    20 mM Tris-HCl based buffer, pH 8.0
    储存条件
    -80 °C,4 °C,-20 °C
    储存方法
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 抗原
    NCAP
    物质类
    Viral Protein
    背景
    Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as tplate for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP ses to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus .
    分子量
    60.3 kDa
    UniProt
    O91743
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