CSNK2A1/CK II alpha Protein (AA 8-350, partial) (His-SUMO Tag)
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- 抗原 See all CSNK2A1/CK II alpha (CSNK2A1) 蛋白
- CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 8-350, partial
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This CSNK2A1/CK II alpha protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- SRARVYAEVN SLRSREYWDY EAHVPSWGNQ DDYQLVRKLG RGKYSEVFEA INITNNERVV VKILKPVKKK KIKREVKILE NLRGGTNIIK LIDTVKDPVS KTPALVFEYI NNTDFKQLYQ ILTDFDIRFY MYELLKALDY CHSKGIMHRD VKPHNVMIDH QQKKLRLIDW GLAEFYHPAQ EYNVRVASRY FKGPELLVDY QMYDYSLDMW SLGCMLASMI FRREPFFHGQ DNYDQLVRIA KVLGTEELYG YLKKYHIDLD PHFNDILGQH SRKRWENFIH SENRHLVSPE ALDLLDKLLR YDHQQRLTAK EAMEHPYFYP VVKEQSQPCA DNAVLSSGLT AAR
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product CSNK2A1 蛋白
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Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391) (Active) protein (GST tag)
CSNK2A1 宿主: 人 宿主: Insect Cells Recombinant SDS, Func Active
Casein Kinase 2 alpha 1 (CSNK2A1) (AA 6-344) protein (His-IF2DI Tag)CSNK2A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391) protein (GST tag)CSNK2A1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-100) protein (GST tag)CSNK2A1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Casein Kinase 2 alpha 1 (CSNK2A1) proteinCSNK2A1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE
Casein Kinase 2 alpha 1 (CSNK2A1) (Active) protein (GST tag,His tag)CSNK2A1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85 % as determined by SDS-PAGE Active
Casein Kinase 2 alpha 1 (CSNK2A1) (Active) protein (GST tag)CSNK2A1 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 93 % as determined by reducing SDS-PAGE. Active
Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391) protein (Strep Tag)Crystallography grade CSNK2A1 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391) protein (Strep Tag)Crystallography grade CSNK2A1 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Casein Kinase 2 alpha 1 (CSNK2A1) (AA 1-391), (full length) protein (His-SUMO Tag)CSNK2A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- CSNK2A1/CK II alpha (CSNK2A1) (Casein Kinase 2 alpha 1 (CSNK2A1))
- 别名
- CSK21 (CSNK2A1 产品)
- 别名
- CK2A2 Protein, CSNK2A1 Protein, CK2A1 Protein, CKII Protein, CSNK2A3 Protein, CK2A Protein, Ck2a Protein, BmCK2a Protein, wu:fi38e04 Protein, wu:fi38h03 Protein, csnk2a1 Protein, CK-II Protein, CK2 Protein, Ckiialpha Protein, Csnk2a1-rs4 Protein, ck2a1 Protein, casein kinase 2 alpha 2 Protein, casein kinase 2 alpha 1 Protein, casein kinase 2 alpha subunit Protein, casein kinase 2, alpha 1 polypeptide Protein, CK2 protein kinase alpha 2 Protein, casein kinase II alpha subunit Protein, Casein kinase II alpha subunit Protein, casein kinase 2, alpha 1 polypeptide S homeolog Protein, CSNK2A2 Protein, CSNK2A1 Protein, ck2a Protein, Ck2a Protein, csnk2a1 Protein, cka2 Protein, Ckiialpha Protein, CK2A1 Protein, Csnk2a1 Protein, csnk2a1.S Protein
- 背景
- Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assbly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV. Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation. Plays an important role in the circadian clock function by phosphorylating ARNTL/BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry.
- 分子量
- 56.6 kDa
- UniProt
- P68400
- 途径
- SARS-CoV-2 Protein Interactome
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