IFNK Protein (AA 24-195) (His tag)
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- 抗原 See all IFNK products
- IFNK (Interferon, kappa (IFNK))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-195
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宿主
- Cow
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资源
- 大肠杆菌（E. Coli）
- 标记
- This IFNK protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- CYLSEDHMLG ARENLRLLAR MNRLSPHPCL QDRKDFGLPQ EMVEGNQLQK DQAISVLHEM LQQCFNLFYT EHSSAAWNTT LLEQLCTGLQ QQLEDLDACL GPVMGEKDSD MGRMGPILTV KKYFQGIHVY LKEKEYSDCA WEIIRVEMMR ALSSSTTLQK RLRKMGGDLN SL
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
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Interferon, kappa (IFNK) (AA 1-207) protein (GST tag)
IFNK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon, kappa (IFNK) (AA 35-129) protein (GST tag)IFNK 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interferon, kappa (IFNK) (AA 28-207) protein (His tag)Crystallography grade IFNK 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Interferon, kappa (IFNK) (AA 22-199) protein (His tag)Crystallography grade IFNK 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- IFNK (Interferon, kappa (IFNK))
- 别名
- IFNT1 (IFNK 产品)
- 别名
- IFNK Protein, IFNT1 Protein, INFE1 Protein, RP11-27J8.1 Protein, interferon kappa Protein, IFNK Protein, Ifnk Protein
- 背景
- Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
- 分子量
- 23.8 kDa
- UniProt
- P15696
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