TARDBP Protein (AA 1-396, partial) (GST tag)
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- 抗原 See all TARDBP 蛋白
- TARDBP (TAR DNA Binding Protein (TARDBP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-396, partial
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TARDBP protein is labelled with GST tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSG
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product TARDBP 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- TARDBP (TAR DNA Binding Protein (TARDBP))
- 别名
- TADBP (TARDBP 产品)
- 别名
- TARDBP Protein, TDP43 Protein, DKFZp459I2127 Protein, tardbp Protein, ALS10 Protein, TDP-43 Protein, 1190002A23Rik Protein, C85084 Protein, Tdp43 Protein, wu:fb77f02 Protein, wu:fc52g10 Protein, TAR DNA binding protein Protein, Tardbp protein Protein, TAR DNA binding protein L homeolog Protein, TAR DNA-binding protein 43-like Protein, TARDBP Protein, tardbp Protein, tardbp.L Protein, Tardbp Protein, LOC100621383 Protein
- 背景
- DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- 分子量
- 70.3 kDa
- UniProt
- Q13148
- 途径
- Positive Regulation of Peptide Hormone Secretion
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