SRY Protein (AA 1-144, partial) (His tag)
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- 抗原 See all SRY 蛋白
- SRY (Sex Determining Region Y (SRY))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-144, partial
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This SRY protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE KRPFFQEAQR LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQ
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product SRY 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- SRY (Sex Determining Region Y (SRY))
- 别名
- SRY (SRY 产品)
- 别名
- SRXX1 Protein, SRXY1 Protein, TDF Protein, TDY Protein, SRYGENE Protein, Sry1 Protein, Sry3BI Protein, Tdf Protein, Tdy Protein, SRY Protein, sex determining region Y Protein, sex determining region of Chr Y Protein, SRY Protein, Sry Protein
- 背景
- Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons . Involved in different aspects of gene regulation including promoter activation or repression. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Promotes DNA bending. Also involved in pre-mRNA splicing . Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.1 Publication
- 分子量
- 21.3 kDa
- UniProt
- Q05738
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