Sortilin 1 Protein (SORT1) (AA 610-754) (His-SUMO Tag)
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- 抗原 See all Sortilin 1 (SORT1) 蛋白
- Sortilin 1 (SORT1)
- 蛋白类型
- Recombinant
- 产品特性
- AA 610-754
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Sortilin 1 protein is labelled with His-SUMO Tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- CEENDYTTWL AHSTDPGDYK DGCILGYKEQ FLRLRKSSVC QNGRDYVVAK QPSICPCSLE DFLCDFGYFR PENASECVEQ PELKGHELEF CLYGKEEHLT TNGYRKIPGD RCQGGMNPAR EVKDLKKKCT SNFLNPKKQN SKSSS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product SORT1 蛋白
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Sortilin 1 (SORT1) (AA 610-754) protein (His tag)
SORT1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Sortilin 1 (SORT1) (AA 532-831) protein (His-IF2DI Tag)SORT1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
Sortilin 1 (SORT1) (AA 203-299) protein (GST tag)SORT1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Sortilin 1 (SORT1) (AA 78-755) protein (His tag)Crystallography grade SORT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sortilin 1 (SORT1) (AA 74-754) protein (His tag)Crystallography grade SORT1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sortilin 1 (SORT1) (AA 78-831) protein (rho-1D4 tag)Crystallography grade SORT1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sortilin 1 (SORT1) (AA 74-825) protein (rho-1D4 tag)Crystallography grade SORT1 宿主: 小鼠 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Sortilin 1 (SORT1) (AA 610-754) protein (His tag)SORT1 宿主: 大鼠 宿主: 酵母菌 Recombinant > 90 % ELISA
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- Sortilin 1 (SORT1)
- 别名
- SORT (SORT1 产品)
- 别名
- SORT1 Protein, 19.m02079 Protein, gp95 Protein, ldlcq6 Protein, sortilin Protein, Gp95 Protein, LDLCQ6 Protein, NT3 Protein, 2900053A11Rik Protein, AI852375 Protein, Ntr3 Protein, Ntsr3 Protein, Nt3 Protein, Nts3 Protein, sort1 Protein, zgc:85953 Protein, sortilin 1 Protein, sortilin Protein, sortilin 1 S homeolog Protein, sortilin 1a Protein, SORT1 Protein, TP01_0016 Protein, BBOV_I002730 Protein, sort1.S Protein, Sort1 Protein, sort1a Protein
- 背景
- Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
- 分子量
- 32.5 kDa
- UniProt
- O54861
- 途径
- Neurotrophin Signaling Pathway
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