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- 抗原 See all PRNP 蛋白
- PRNP (Prion Protein (PRNP))
- 蛋白类型
- Recombinant
- 产品特性
- AA 29-231
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宿主
- 大鼠
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PRNP protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- GGWNTGGSRY PGQGSPGGNR YPPQSGGTWG QPHGGGWGQP HGGGWGQPHG GGWGQPHGGG WSQGGGTHNQ WNKPSKPKTN LKHVAGAAAA GAVVGGLGGY MLGSAMSRPM LHFGNDWEDR YYRENMYRYP NQVYYRPVDQ YSNQNNFVHD CVNITIKQHT VTTTTKGENF TETDVKMMER VVEQMCVTQY QKESQAYYDG RRS
- 纯化方法
- SDS-PAGE
- 纯度
- > 90 %
- Top Product
- Discover our top product PRNP 蛋白
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Prion Protein (PRNP) (AA 23-230) protein (Fc Tag)
PRNP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Prion Protein (PRNP) (AA 23-230) protein (Fc Tag)PRNP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Prion Protein (PRNP) (AA 1-253) protein (GST tag)PRNP 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Prion Protein (PRNP) (AA 1-73) protein (Strep Tag)Crystallography grade PRNP 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Prion Protein (PRNP) proteinPRNP 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % ELISA, SDS, WB, IP
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.1-2 mg/mL
- 缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
- 储存条件
- -80 °C,4 °C,-20 °C
- 储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- 抗原
- PRNP (Prion Protein (PRNP))
- 别名
- PRIO (PRNP 产品)
- 别名
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ASCR Protein, AltPrP Protein, CD230 Protein, CJD Protein, GSS Protein, KURU Protein, PRIP Protein, PrP Protein, PrP27-30 Protein, PrP33-35C Protein, PrPc Protein, p27-30 Protein, Prn Protein, Prn-p Protein, prp Protein, cjd Protein, prion Protein, prp(c) Protein, MGC84114 Protein, PRP Protein, PRPC Protein, Prp Protein, SIP Protein, PRNP Protein, AA960666 Protein, AI325101 Protein, PrP
Protein, PrPC Protein, PrPSc Protein, Prn-i Protein, Sinc Protein, prP27-30 Protein, prP33-35C Protein, PrP-1 Protein, PrP1 Protein, prnprs1 Protein, stPrP-1 Protein, zgc:123004 Protein, prion protein Protein, prion protein S homeolog Protein, prion protein b Protein, PRNP Protein, Prnp Protein, prnp.S Protein, prnpb Protein - 背景
- May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu2+ or ZN2+ for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains .
- 分子量
- 26.34 kDa
- UniProt
- P13852
- 途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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